User profiles for Yi-Ping Fu

Yi-Ping Fu

National Heart, Lung, and Blood Institute, NIH
Verified email at mail.nih.gov
Cited by 2592

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci

…, M Kogevinas, A Hutchinson, Z Wang, YP Fu… - Nature …, 2010 - nature.com
We conducted a multi-stage, genome-wide association study of bladder cancer with a
primary scan of 591,637 SNPs in 3,532 affected individuals (cases) and 5,120 controls of …

Effect of genotype-guided oral P2Y12 inhibitor selection vs conventional clopidogrel therapy on ischemic outcomes after percutaneous coronary intervention: the …

…, P Gordon, JD Abbott, C Cagin, L Baudhuin, YP Fu… - Jama, 2020 - jamanetwork.com
Importance After percutaneous coronary intervention (PCI), patients withCYP2C19*2or*3loss-of-function
(LOF) variants treated with clopidogrel have increased risk of ischemic events. …

Breast cancer risk associated with genotypic polymorphism of the nonhomologous end-joining genes: a multigenic study on cancer susceptibility

YP Fu, JC Yu, TC Cheng, MA Lou, GC Hsu, CY Wu… - Cancer research, 2003 - AACR
The role of the familial breast cancer susceptibility genes, BRCA1 and BRCA2, in the
homologous recombination pathway for DNA double-strand break (DSB) repair suggests that the …

Clopidogrel pharmacogenetics: state-of-the-art review and the TAILOR-PCI Study

…, A Lerman, A Hasan, E Iturriaga, YP Fu… - Circulation …, 2019 - Am Heart Assoc
Common genetic variation in CYP2C19 (cytochrome P450, family 2, subfamily C, polypeptide
19) *2 and *3 alleles leads to a loss of functional protein, and carriers of these loss-of-…

Common genetic polymorphisms modify the effect of smoking on absolute risk of bladder cancer

…, I De Vivo, D Albanes, MP Purdue, S Sharma, YP Fu… - Cancer research, 2013 - AACR
Bladder cancer results from the combined effects of environmental and genetic factors, smoking
being the strongest risk factor. Evaluating absolute risks resulting from the joint effects of …

[HTML][HTML] Identification of diabetic retinopathy genes through a genome-wide association study among Mexican-Americans from Starr County, Texas

YP Fu, DM Hallman, VH Gonzalez, BEK Klein… - Journal of …, 2009 - hindawi.com
To identify genetic loci for severe diabetic retinopathy, 286 Mexican-Americans with type 2
diabetes from Starr County, Texas, completed physical examinations including fundus …

A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3

…, J Gu, X Pu, A Hutchinson, YP Fu… - Human molecular …, 2011 - academic.oup.com
Genome-wide and candidate-gene association studies of bladder cancer have identified 10
susceptibility loci thus far. We conducted a meta-analysis of two previously published …

Breast Cancer Risk and the DNA Double-Strand Break End-Joining Capacity of Nonhomologous End-Joining Genes Are Affected by BRCA1

DT Bau, YP Fu, ST Chen, TC Cheng, JC Yu, PE Wu… - Cancer research, 2004 - AACR
A tumorigenic role of the nonhomologous end-joining (NHEJ) pathway for the repair of DNA
double-strand breaks (DSBs) has been suggested by the finding of a significant association …

Common genetic variants in the PSCA gene influence gene expression and bladder cancer risk

YP Fu, I Kohaar, N Rothman, J Earl… - Proceedings of the …, 2012 - National Acad Sciences
Genome-wide association studies have identified a SNP, rs2294008, on 8q24.3 within the
prostate stem cell antigen (PSCA) gene, as a risk factor for bladder cancer. To fine-map this …

Sunlight, polymorphisms of vitamin D-related genes and risk of breast cancer

…, DM Freedman, P Bhatti, MM Doody, YP Fu… - Anticancer …, 2013 - ar.iiarjournals.org
Background/Aim: Geographic gradients in breast cancer incidence and mortality suggest
that vitamin D may reduce risk. The enzyme 25-hydroxyvitamin D 24-hydroxylase (CYP24A1), …