Cancer progression is commonly segregated into processes of primary tumour growth and
secondary metastasis. Recent evidence suggests that a subpopulation of cancer cells, cancer …

MicroRNAs (miRNAs) influence many biological processes, including cancer. They do so by
posttranscriptionally repressing target mRNAs to which they have sequence …

Endoplasmic reticulum (ER) stress-associated apoptosis plays a role in organ remodeling
after insult. The effect of ER stress on renal tubular damage and fibrosis remains controversial. …

Epithelial–mesenchymal transition (EMT)/mesenchymal–epithelial transition (MET) processes
are proposed to be a driving force of cancer metastasis. By studying metastasis in bone …

Osteoporosis is one of the most common bone pathologies. A number of novel molecules
have been reported to increase bone formation including cysteine-rich protein 61 (CYR61), a …

Vascular endothelial growth factor C (VEGF-C) has been identified as a multifaceted factor
participating in the regulation of tumor angiogenesis and lymphangiogenesis. VEGF-C is not …

Objective. The purpose of this study was to develop a mathematical method to determine
optimum muscle length and muscle stress based on the measurable physiological and …

Wnt signaling contributes to the reprogramming and maintenance of cancer stem cell (CSC)
states that are activated by epithelial–mesenchymal transition (EMT). However, the …

Therapy with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs,
such as gefitinib or erlotinib) significantly prolongs survival time for patients with tumors …

Polycystic ovary syndrome (PCOS) is a common endocrinopathy, characterized by chronic
anovulation, hyperandrogenism, and multiple small subcapsular cystic follicles in the ovary …