User profiles for Yichen Lu

Yichen Lu

- Verified email at alumni.upenn.edu - Cited by 859

Yichen Lu

- Verified email at jiangnan.edu.cn - Cited by 418

[HTML][HTML] Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian–human immunodeficiency virus infection

…, TA Rizvi, R Schmidt, LR Hill, ME Keeling, Y Lu… - Nature medicine, 2000 - nature.com
Although maternal human immunodeficiency virus type 1 (HIV-1) transmission occurs during
gestation, intrapartum and postpartum (by breast-feeding), 50–70% of all infected children …

Protection of macaques against pathogenic simian/human immunodeficiency virus 89.6 PD by passive transfer of neutralizing antibodies

…, CR Brown, CV Sapan, SS Frankel, Y Lu… - Journal of …, 1999 - Am Soc Microbiol
The role of antibody in protection against human immunodeficiency virus (HIV-1) has been
difficult to study in animal models because most primary HIV-1 strains do not infect …

High-rate quantum key distribution exceeding 110 Mb s–1

W Li, L Zhang, H Tan, Y Lu, SK Liao, J Huang, H Li… - Nature …, 2023 - nature.com
Quantum key distribution (QKD) can provide fundamentally proven secure communication.
Towards application, the secret key rate (SKR) is a key figure of merit for any QKD system. …

[HTML][HTML] Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm

…, C Jiang, J Fang, Q Liu, D Zong, W Zhang, Y Lu… - Nature …, 2020 - nature.com
Several studies show that the immunosuppressive drugs targeting the interleukin-6 (IL-6)
receptor, including tocilizumab, ameliorate lethal inflammatory responses in COVID-19 patients …

[HTML][HTML] Flexible neural electrode array based-on porous graphene for cortical microstimulation and sensing

Y Lu, H Lyu, AG Richardson, TH Lucas, D Kuzum - Scientific reports, 2016 - nature.com
Neural sensing and stimulation have been the backbone of neuroscience research, brain-machine
interfaces and clinical neuromodulation therapies for decades. To-date, most of the …

Energy-efficient Mott activation neuron for full-hardware implementation of neural networks

S Oh, Y Shi, J Del Valle, P Salev, Y Lu, Z Huang… - Nature …, 2021 - nature.com
To circumvent the von Neumann bottleneck, substantial progress has been made towards in-memory
computing with synaptic devices. However, compact nanodevices implementing …

[HTML][HTML] Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex

MN Wilson, M Thunemann, X Liu, Y Lu, F Puppo… - Nature …, 2022 - nature.com
Human cortical organoids, three-dimensional neuronal cultures, are emerging as powerful
tools to study brain development and dysfunction. However, whether organoids can …

Defining user experience goals to guide the design of industrial systems

…, T Keskinen, H Koskinen, Y Lu… - Behaviour & …, 2015 - Taylor & Francis
The key prerequisite for experience-driven design is to define what experience to design for.
User experience (UX) goals concretise the intended experience. Based on our own case …

[HTML][HTML] Deep 2-photon imaging and artifact-free optogenetics through transparent graphene microelectrode arrays

M Thunemann, Y Lu, X Liu, K Kılıç, M Desjardins… - Nature …, 2018 - nature.com
Recent advances in optical technologies such as multi-photon microscopy and optogenetics
have revolutionized our ability to record and manipulate neuronal activity. Combining …

Structure of a SIN3–HDAC complex from budding yeast

Z Guo, C Chu, Y Lu, X Zhang, Y Xiao, M Wu… - Nature Structural & …, 2023 - nature.com
SIN3–HDAC (histone deacetylases) complexes have important roles in facilitating local histone
deacetylation to regulate chromatin accessibility and gene expression. Here, we present …