User profiles for Yifan Cheng
Yifan ChengUniversity of California San Francisco Verified email at ucsf.edu Cited by 34293 |
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
… Yifan Cheng … Shawn Q Zheng, Yifan Cheng & David A Agard … Yifan Cheng …
[HTML][HTML] Structure of the TRPV1 ion channel determined by electron cryo-microscopy
Transient receptor potential (TRP) channels are sensors for a wide range of cellular and
environmental signals, but elucidating how these channels respond to physical and chemical …
environmental signals, but elucidating how these channels respond to physical and chemical …
[HTML][HTML] Single-particle cryo-EM at crystallographic resolution
Y Cheng - Cell, 2015 - cell.com
Until only a few years ago, single-particle electron cryo-microscopy (cryo-EM) was usually
not the first choice for many structural biologists due to its limited resolution in the range of …
not the first choice for many structural biologists due to its limited resolution in the range of …
Single-particle cryo-EM—How did it get here and where will it go
Y Cheng - Science, 2018 - science.org
Cryo–electron microscopy, or simply cryo-EM, refers mainly to three very different yet
closely related techniques: electron crystallography, single-particle cryo-EM, and electron …
closely related techniques: electron crystallography, single-particle cryo-EM, and electron …
Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM
…, MB Braunfeld, S Gubbens, DA Agard, Y Cheng - Nature …, 2013 - nature.com
In recent work with large high-symmetry viruses, single-particle electron cryomicroscopy (cryo-EM)
has achieved the determination of near-atomic-resolution structures by allowing …
has achieved the determination of near-atomic-resolution structures by allowing …
Structure of the TRPA1 ion channel suggests regulatory mechanisms
The TRPA1 ion channel (also known as the wasabi receptor) is a detector of noxious chemical
agents encountered in our environment or produced endogenously during tissue injury or …
agents encountered in our environment or produced endogenously during tissue injury or …
[HTML][HTML] Structure of the human transferrin receptor-transferrin complex
Iron, insoluble as free Fe 3+ and toxic as free Fe 2+ , is distributed through the body as Fe 3+
bound to transferrin (Tf) for delivery to cells by endocytosis of its complex with transferrin …
bound to transferrin (Tf) for delivery to cells by endocytosis of its complex with transferrin …
[PDF][PDF] A primer to single-particle cryo-electron microscopy
Cryo-electron microscopy (cryo-EM) of single-particle specimens is used to determine the
structure of proteins and macromolecular complexes without the need for crystals. Recent …
structure of proteins and macromolecular complexes without the need for crystals. Recent …
TRPV1 structures in distinct conformations reveal activation mechanisms
Transient receptor potential (TRP) channels are polymodal signal detectors that respond to
a wide range of physical and chemical stimuli. Elucidating how these channels integrate and …
a wide range of physical and chemical stimuli. Elucidating how these channels integrate and …
[PDF][PDF] Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases
Substrates enter the cylindrical 20S proteasome through a gated channel that is regulated
by the ATPases in the 19S regulatory particle in eukaryotes or the homologous PAN ATPase …
by the ATPases in the 19S regulatory particle in eukaryotes or the homologous PAN ATPase …