Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion
…, D Jhutty, CM Nemec, J Wang, L Wang, Y Yin… - Nature …, 2019 - nature.com
Understanding complex tissues requires single-cell deconstruction of gene regulation with
precision and scale. Here, we assess the performance of a massively parallel droplet-based …
precision and scale. Here, we assess the performance of a massively parallel droplet-based …
Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex
…, MN Tran, Z Besich, M Tippani, J Chew, Y Yin… - BioRxiv, 2020 - biorxiv.org
We used the 10x Genomics Visium platform to define the spatial topography of gene expression
in the six-layered human dorsolateral prefrontal cortex (DLPFC). We identified extensive …
in the six-layered human dorsolateral prefrontal cortex (DLPFC). We identified extensive …
GeoChip 3.0 as a high-throughput tool for analyzing microbial community composition, structure and functional activity
…, M Xu, CL Hemme, X Li, L Wu, TJ Gentry, Y Yin… - The ISME …, 2010 - academic.oup.com
A new generation of functional gene arrays (FGAs; GeoChip 3.0) has been developed, with
∼28 000 probes covering approximately 57 000 gene variants from 292 functional gene …
∼28 000 probes covering approximately 57 000 gene variants from 292 functional gene …
[HTML][HTML] LoAdaBoost: Loss-based AdaBoost federated machine learning with reduced computational complexity on IID and non-IID intensive care data
Intensive care data are valuable for improvement of health care, policy making and many
other purposes. Vast amount of such data are stored in different locations, on many different …
other purposes. Vast amount of such data are stored in different locations, on many different …
Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex
…, MN Tran, Z Besich, M Tippani, J Chew, Y Yin… - Nature …, 2021 - nature.com
We used the 10x Genomics Visium platform to define the spatial topography of gene expression
in the six-layered human dorsolateral prefrontal cortex. We identified extensive layer-…
in the six-layered human dorsolateral prefrontal cortex. We identified extensive layer-…
Prediction algorithm for network security situation based on bp neural network optimized by sa-soa
R Zhang, M Liu, Y Yin, Q Zhang, Z Cai - International Journal of …, 2020 - ijpe-online.com
Abstract: Network security situation prediction has been a major research focus in the field
of network security in recent years. It can predict the future network security status and its …
of network security in recent years. It can predict the future network security status and its …
[HTML][HTML] Single-cell sequencing of genomic DNA resolves sub-clonal heterogeneity in a melanoma cell line
…, J Sorenson, IT Fiddes, V Kumar, Y Yin… - Communications …, 2020 - nature.com
We performed shallow single-cell sequencing of genomic DNA across 1475 cells from a cell-line,
COLO829, to resolve overall complexity and clonality. This melanoma tumor-line has …
COLO829, to resolve overall complexity and clonality. This melanoma tumor-line has …
Identification of functional paralog shift mutations: Conversion of Escherichia coli malate dehydrogenase to a lactate dehydrogenase
Y Yin, JF Kirsch - Proceedings of the National Academy of …, 2007 - National Acad Sciences
Five positions in the Escherichia coli malate dehydrogenase (eMDH) sequence, which
distinguish MDH from lactate dehydrogenase (LDH) activity, were identified through a …
distinguish MDH from lactate dehydrogenase (LDH) activity, were identified through a …
[HTML][HTML] Sc-compReg enables the comparison of gene regulatory networks between conditions using single-cell data
…, J Xin, F Meschi, ML Li, CM Nemec, Y Yin… - Nature …, 2021 - nature.com
The comparison of gene regulatory networks between diseased versus healthy individuals
or between two different treatments is an important scientific problem. Here, we propose sc-…
or between two different treatments is an important scientific problem. Here, we propose sc-…
Comparison of primary suture and T-tube drainage after laparoscopic common bile duct exploration combined with intraoperative choledochoscopy in the treatment of …
Y Yin, K He, X Xia - Journal of Laparoendoscopic & Advanced …, 2022 - liebertpub.com
Objective: To compare the safety and feasibility of T-tube drainage and primary suture after
laparoscopy combined with choledochoscopy in the treatment of secondary …
laparoscopy combined with choledochoscopy in the treatment of secondary …