Major depressive disorder (MDD) is a common complex trait with enormous public health
significance. As part of the Genetic Association Information Network initiative of the US …

Objectives : We evaluated whether carotid intima-media thickness (CIMT) and the presence
or absence of plaque improved coronary heart disease (CHD) risk prediction when added to …

As RNA-seq is replacing gene expression microarrays to assess genome-wide transcription
abundance, gene expression Quantitative Trait Locus (eQTL) studies using RNA-seq have …

This paper investigates a remanufacturing closed-loop supply chain under the cap-and-trade
regulation, where the collecting operations can be carried out by a manufacturer or a …

BACKGROUND. The identification and treatment of individuals with tuberculosis (TB) is a
global public health priority. Accurate diagnosis of pulmonary active TB (ATB) disease remains …

Background and Purpose— Inflammation plays a critical role in the development of vascular
disease, and increased levels of the inflammatory biomarkers, lipoprotein-associated …

Approaches exploiting trait distribution extremes may be used to identify loci associated
with common traits, but it is unknown whether these loci are generalizable to the broader …

We tested the hypothesis that extracellular haem is linked to the incidence of acute complications
of sickle cell disease ( SCD ). Using multivariable regression analysis, higher plasma …

One of the roadblocks to developing effective therapeutics for Huntington disease (HD) is the
lack of animal models that develop progressive clinical traits comparable to those seen in …

Complex and dynamic networks of molecules are involved in human diseases. High-throughput
technologies enable omics studies interrogating thousands to millions of makers with …