User profiles for Yin Peng

Peng Yin

Professor of Systems Biology
Verified email at hms.harvard.edu
Cited by 19074

Three-dimensional structures self-assembled from DNA bricks

Y Ke, LL Ong, WM Shih, P Yin - science, 2012 - science.org
We describe a simple and robust method to construct complex three-dimensional (3D)
structures by using short synthetic DNA strands that we call “DNA bricks.” In one-step annealing …

[HTML][HTML] Yin Yang 1 is a negative regulator of p53

G Sui, EB Affar, Y Shi, C Brignone, NR Wall, P Yin… - Cell, 2004 - cell.com
Yin Yang 1 (YY1) is a transcription factor that plays an essential role in development. However,
the full spectrum of YY1's functions and mechanism of action remains unclear. We find …

Complex shapes self-assembled from single-stranded DNA tiles

B Wei, M Dai, P Yin - Nature, 2012 - nature.com
Programmed self-assembly of strands of nucleic acid has proved highly effective for creating
a wide range of structures with desired shapes 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , …

[HTML][HTML] Mortality, morbidity, and risk factors in China and its provinces, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

M Zhou, H Wang, X Zeng, P Yin, J Zhu, W Chen, X Li… - The Lancet, 2019 - thelancet.com
Background Public health is a priority for the Chinese Government. Evidence-based decision
making for health at the province level in China, which is home to a fifth of the global …

Global estimates of mortality associated with long-term exposure to outdoor fine particulate matter

…, PJ Villeneuve, AB Miller, P Yin… - Proceedings of the …, 2018 - National Acad Sciences
Exposure to ambient fine particulate matter (PM 2.5 ) is a major global health concern.
Quantitative estimates of attributable mortality are based on disease-specific hazard ratio models …

Programming biomolecular self-assembly pathways

P Yin, HMT Choi, CR Calvert, NA Pierce - Nature, 2008 - nature.com
In nature, self-assembling and disassembling complexes of proteins and nucleic acids bound
to a variety of ligands perform intricate and diverse dynamic functions. In contrast, attempts …

[HTML][HTML] Cause-specific mortality for 240 causes in China during 1990–2013: a systematic subnational analysis for the Global Burden of Disease Study 2013

…, W Chen, L Wang, S Liu, Y Li, L Wang, Y Liu, P Yin… - The Lancet, 2016 - thelancet.com
Background China has experienced a remarkable epidemiological and demographic transition
during the past three decades. Far less is known about this transition at the subnational …

Sulfur-anchoring synthesis of platinum intermetallic nanoparticle catalysts for fuel cells

CL Yang, LN Wang, P Yin, J Liu, MX Chen, QQ Yan… - Science, 2021 - science.org
Atomically ordered intermetallic nanoparticles are promising for catalytic applications but
are difficult to produce because the high-temperature annealing required for atom ordering …

Programmable self-assembly of three-dimensional nanostructures from 10,000 unique components

…, C Myhrvold, A Zhu, R Jungmann, G Bellot, Y Ke, P Yin - Nature, 2017 - nature.com
Nucleic acids (DNA and RNA) are widely used to construct nanometre-scale structures with
ever increasing complexity 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , with possible …

Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT

…, JB Woehrstein, M Dai, WM Shih, P Yin - Nature …, 2014 - nature.com
Super-resolution fluorescence microscopy is a powerful tool for biological research, but
obtaining multiplexed images for a large number of distinct target species remains challenging. …