Valvular heart diseases are the third leading cause of cardiovascular disease, resulting in
more than 25,000 deaths annually in the United States. Heart valve tissue engineering (HVTE) …

Valvular heart disease is an important source of cardiovascular morbidity and mortality. Current
prosthetic valve replacement options, such as bioprosthetic and mechanical heart valves …

Materials currently used to repair or replace a heart valve are not durable. Their limited durability
related to structural degeneration or thrombus formation is attributed to their inadequate …

Aims Bioprosthetic heart valves (BHVs), made from glutaraldehyde-fixed heterograft materials,
are subject to more rapid structural valve degeneration (SVD) in paediatric and young …

Bioprosthetic heart valves (BHVs) largely circumvent the need for long‐term anticoagulation
compared with mechanical valves but are increasingly susceptible to deterioration and …

Cerium oxide nanoparticles (CNPs) represent a promising class of antioxidant nanoparticles
with potential therapeutic value. Due to the easily reversible oxidation states of cerium (Ce 3…

Despite significant interest in developing extracellular matrix (ECM)‐inspired biomaterials to
recreate native cell‐instructive microenvironments, the major challenge in the biomaterial …

Myoblast differentiation is a key step in myogenesis and has long been considered to be
controlled mainly by biochemical cues such as growth factors. However, the tissue engineering …

Valvular heart diseases are associated with significant cardiovascular morbidity and mortality,
and often require surgical and/or percutaneous repair or replacement. Valve replacement …

Biomaterials have gained tremendous attention in regenerative medicine and tissue
engineering applications due to their ability to enhance functional tissue regeneration. After …