Background: The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed great threat to human health. …

It is unclear whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can
directly infect human kidney, thus leading to acute kidney injury (AKI). Here, we perform a …

While lymphocytopenia is a common characteristic of patients infected by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the mechanisms responsible for …

10.7554/eLife.47454.001 Mechanical load of the skeleton system is essential for the
development, growth, and maintenance of bone. However, the molecular mechanism by which …

Background Thymosin alpha 1 (Tα1) had been used in the treatment of viral infections as an
immune response modifier for many years. However, clinical benefits and the mechanism of …

The neuromuscular junction (NMJ) is a peripheral synaptic connection between presynaptic
motor neurons and postsynaptic skeletal muscle fibers that enables muscle contraction and …

Transition‐metal atomic site catalysts (ASCs) are a new class of catalytic system for CO 2
electroreduction, however, their practical application is greatly hindered by the challenge that …

Background. We previously reported that lymphocytopenia and T cell exhaustion is notable
in acute COVID19 patients, especially in aged and severe cases. Thymosin alpha 1 (Tα1) …

Mechanical stimulation plays an important role in bone remodeling. Exercise-induced
mechanical loading enhances bone strength, whereas mechanical unloading leads to bone loss. …

Osteoclast over-activation leads to bone loss and chloride homeostasis is fundamental
importance for osteoclast function. The calcium-activated chloride channel Anoctamin 1 (also …