[HTML][HTML] Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice
…, S Yu, S Feng, E Stypulkowski, Y Guan… - The Journal of …, 2012 - Am Soc Clin Investig
The constant self renewal and differentiation of adult intestinal stem cells maintains a
functional intestinal mucosa for a lifetime. However, the molecular mechanisms that regulate …
functional intestinal mucosa for a lifetime. However, the molecular mechanisms that regulate …
Phosphodiesterases coordinate cAMP propagation induced by two stimulatory G protein-coupled receptors in hearts
Inflammation is a significant player in the progression of heart failure and has detrimental
effects on cardiac function. Prostaglandin (PG)E2, a major proinflammatory prostanoid in the …
effects on cardiac function. Prostaglandin (PG)E2, a major proinflammatory prostanoid in the …
[HTML][HTML] Klotho regulated by estrogen plays a key role in sex differences in stress resilience in rats
Z Tan, Y Li, Y Guan, J Iqbal, C Wang, R Yan… - International Journal of …, 2023 - mdpi.com
Klotho (KL) is a glycosyl hydrolase and aging-suppressor gene. Stress is a risk factor for
depression and anxiety, which are highly comorbid with each other. The aim of this study is to …
depression and anxiety, which are highly comorbid with each other. The aim of this study is to …
Enhanced basal contractility but reduced excitation-contraction coupling efficiency and β-adrenergic reserve of hearts with increased Cav1. 2 activity
M Tang, X Zhang, Y Li, Y Guan, X Ai… - American Journal …, 2010 - journals.physiology.org
Cardiac remodeling during heart failure development induces a significant increase in the
activity of the L-type Ca 2+ channel (Cav1.2). However, the effects of enhanced Cav1.2 activity …
activity of the L-type Ca 2+ channel (Cav1.2). However, the effects of enhanced Cav1.2 activity …
A balance of outward and linear inward ionic currents is required for generation of slow-wave oscillations
J Golowasch, A Bose, Y Guan… - Journal of …, 2017 - journals.physiology.org
Regenerative inward currents help produce slow oscillations through a negative-slope
conductance region of their current-voltage relationship that is well approximated by a linear …
conductance region of their current-voltage relationship that is well approximated by a linear …
The role of linear and voltage-dependent ionic currents in the generation of slow wave oscillations
Neuronal oscillatory activity is generated by a combination of ionic currents, including at least
one inward regenerative current that brings the cell towards depolarized voltages and one …
one inward regenerative current that brings the cell towards depolarized voltages and one …
[HTML][HTML] Advances in coatings on biodegradable magnesium alloys
…, WC Qi, RC Zeng, XB Chen, CD Gu, SK Guan… - Journal of Magnesium …, 2020 - Elsevier
The clinic applications of bioabsorbable magnesium (Mg) and its alloys have been significantly
restricted owing to their poor corrosion resistance. Besides elemental alloying, surface …
restricted owing to their poor corrosion resistance. Besides elemental alloying, surface …
Prevalence of vision impairment in older adults in rural China: the China Nine-Province Survey
J Zhao, LB Ellwein, H Cui, J Ge, H Guan, J Lv, X Ma… - Ophthalmology, 2010 - Elsevier
PURPOSE: Describe the prevalence of visual impairment/blindness among older adults in
rural populations in China. DESIGN: Population-based, cross-sectional study. PARTICIPANTS…
rural populations in China. DESIGN: Population-based, cross-sectional study. PARTICIPANTS…
Prevalence and outcomes of cataract surgery in rural China: the China nine-province survey
J Zhao, LB Ellwein, H Cui, J Ge, H Guan, J Lv, X Ma… - Ophthalmology, 2010 - Elsevier
PURPOSE: To investigate the prevalence and visual acuity (VA) outcomes of cataract surgery
in rural populations throughout China. DESIGN: Population-based, cross-sectional study. …
in rural populations throughout China. DESIGN: Population-based, cross-sectional study. …
Corrosion behavior characterization of as extruded Mg-8Li-3Al alloy with minor alloying elements (Gd, Sn and Cu) by scanning Kelvin probe force microscopy
…, K Wang, Q Liu, P Sun, H Yan, H Song, C Luo, H Guan… - Corrosion …, 2020 - Elsevier
The effects of Gd, Sn and Cu on the corrosion behavior of as extruded Mg–8Li–3Al (LA83)
alloy were characterized by scanning Kelvin probe force microscopy, weight loss, hydrogen …
alloy were characterized by scanning Kelvin probe force microscopy, weight loss, hydrogen …