Recently, the treatment of stroke has focused on antioxidant therapies, where oxidative stress
is implicated. The preventive and therapeutic potential of plant compounds on ischemic …

Emerging evidence suggests that endothelial activation plays a central role in the pathogenesis
of acute respiratory distress syndrome (ARDS) and multiorgan failure in patients with …

Mitochondria are high dynamic organelles with frequent fission and fusion. Here, we found
hypoxia stimulated Drp1 expression, mitochondrial fission and migration in metastatic MDA-…

Maslinic acid (2-α, 3-β-dihydroxyolean-12-en-28-oic acid) is a natural triterpenoid
compound from Olea europaea. This compound prevents oxidative stress and pro-inflammatory …

Endothelial activation plays an essential role in the pathogenesis of sepsis-induced acute
lung injury, however, the detailed regulatory mechanisms remain largely unknown. Here, we …

… Qian Liu did a part of the western blot assay and analyzed the study data. Yisong Qian
performed real-time PCR experiments and contributed to the collecting and analyzing the data. …

Maslinic acid (MA), a natural triterpene from Olea europaea L., is a well‐known inhibitor of
glycogen phosphorylase and elicits multiple biological activities. The purpose of this study …

COVID-19 is a highly infectious respiratory disease caused by a new coronavirus known as
SARS-CoV-2. COVID-19 is characterized by progressive respiratory failure resulting from …

Myocardial ischemic/reperfusion injury results from severe impairment of coronary blood
supply and leads to irreversible cell death, with limited therapeutic possibilities. Asiatic acid is a …

The innate immune response, which is tightly regulated by Toll-like receptor 4 (TLR4)
pathway, has been shown to play a critical role in brain damage following cerebral ischemia-…