User profiles for Yiu Yiu Lee
 | Yiu Yiu LeeVerified email at connect.hku.hk Cited by 549 |
Isoprostanes, neuroprostanes and phytoprostanes: An overview of 25 years of research in chemistry and biology
JM Galano, YY Lee, C Oger, C Vigor… - Progress in lipid …, 2017 - Elsevier
Since the beginning of the 1990's diverse types of metabolites originating from
polyunsaturated fatty acids, formed under autooxidative conditions were discovered. Known as …
polyunsaturated fatty acids, formed under autooxidative conditions were discovered. Known as …
[HTML][HTML] Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain
Exogenous metabolites from microbial and dietary origins have profound effects on host
metabolism. Here, we report that a sub-population of lipid droplets (LDs), which are conserved …
metabolism. Here, we report that a sub-population of lipid droplets (LDs), which are conserved …
Synthesis, discovery, and quantitation of dihomo‐isofurans: biomarkers for in vivo adrenic acid peroxidation
A de La Torre, YY Lee, C Oger, PT Sangild… - Angewandte …, 2014 - Wiley Online Library
The growing importance of lipidomics, and the interest of non‐enzymatic metabolites of
polyunsaturated fatty acids (PUFAs) prompted us to initiate the synthesis of novel dihomo‐IsoF …
polyunsaturated fatty acids (PUFAs) prompted us to initiate the synthesis of novel dihomo‐IsoF …
Total syntheses and in vivo quantitation of novel neurofuran and dihomo‐isofuran derived from docosahexaenoic acid and adrenic acid
A de La Torre, YY Lee, A Mazzoni… - … A European Journal, 2015 - Wiley Online Library
Neurofurans (NeuroFs) and dihomo‐isofurans (dihomo‐IsoFs) are produced in vivo by non‐enzymatic
free‐radical pathways from docosahexaenoic and adrenic acids, respectively. As …
free‐radical pathways from docosahexaenoic and adrenic acids, respectively. As …
Nonenzymatic oxygenated metabolite of docosahexaenoic acid, 4(RS)‐4‐F4t‐neuroprostane, acts as a bioactive lipid molecule in neuronal cells
YY Lee, JM Galano, HH Leung, L Balas, C Oger… - FEBS …, 2020 - Wiley Online Library
Docosahexaenoic acid (DHA), an abundant fatty acid in the brain, is susceptible to auto‐oxidation
in situ and releases metabolites such as F 4 ‐neuroprostane (4‐F 4t ‐NeuroP). The …
in situ and releases metabolites such as F 4 ‐neuroprostane (4‐F 4t ‐NeuroP). The …
The novelty of phytofurans, isofurans, dihomo-isofurans and neurofurans: Discovery, synthesis and potential application
C Cuyamendous, A de La Torre, YY Lee, KS Leung… - Biochimie, 2016 - Elsevier
… Later, the combined groups of Galano/Durand and Lee discovered the dihomo-IsoFs derived
from AdA in pig brain [9]. Recently, this join collaborative effort also identified the PhytoFs …
from AdA in pig brain [9]. Recently, this join collaborative effort also identified the PhytoFs …
Extra virgin olive oil reduced polyunsaturated fatty acid and cholesterol oxidation in rodent liver: is this accounted for hydroxytyrosol-fatty acid conjugation?
The effects of extra virgin olive oil (EVOO) and carbon tetrachloride (CCl 4 ) induced oxidative
stress in rats were determined by the generation of isoprostanoids. These are known to be …
stress in rats were determined by the generation of isoprostanoids. These are known to be …
Special Issue on “Analytical Methods for Oxidized Biomolecules and Antioxidants” The use of isoprostanoids as biomarkers of oxidative damage, and their role in …
… Recently, Lee and Durand's groups also showed the presence of these compounds in preterm
pig brains [Citation25], together with their isofuranoid (IsoF) equivalents. Additionally, the …
pig brains [Citation25], together with their isofuranoid (IsoF) equivalents. Additionally, the …
Assessment of isoprostanes in human plasma: technical considerations and the use of mass spectrometry
YY Lee, JM Galano, C Oger, C Vigor, R Guillaume… - Lipids, 2016 - Springer
Oxygenated lipid mediators released from non-enzymatic peroxidation of polyunsaturated
fatty acids (PUFA) are known to have functional roles in humans. Notably, among these lipid …
fatty acids (PUFA) are known to have functional roles in humans. Notably, among these lipid …
Prenatal exposure to the contaminant perfluorooctane sulfonate elevates lipid peroxidation during mouse fetal development but not in the pregnant dam
Perfluorooctane sulfonate (PFOS), a member of the perfluorinated chemical family, has been
convincingly demonstrated to affect lipid metabolism in animals and humans and readily …
convincingly demonstrated to affect lipid metabolism in animals and humans and readily …