pH‐controlled histone acetylation amplifies melanocyte differentiation downstream of MITF

DA Raja, V Gotherwal, SA Burse, YJ Subramaniam… - EMBO …, 2020 - embopress.org
Tanning response and melanocyte differentiation are mediated by the central transcription
factor MITF . This involves the rapid and selective induction of melanocyte maturation genes, …

Histone variant dictates fate biasing of neural crest cells to melanocyte lineage

DA Raja, Y Subramaniam, A Aggarwal… - …, 2020 - journals.biologists.com
In the neural crest lineage, progressive fate restriction and stem cell assignment are crucial
for both development and regeneration. Whereas fate commitment events have distinct …

Sustained pigmentation causes DNA damage and invokes translesion polymerase Polκ for repair in melanocytes

M Ghazi, S Khanna, Y Subramaniam… - Nucleic Acids …, 2023 - academic.oup.com
Melanin protects skin cells from ultraviolet radiation-induced DNA damage. However,
intermediates of eumelanin are highly reactive quinones that are potentially genotoxic. In this study…

Migration and establishment of progenitor pool of melanocytes is governed by SEMA3E-PLXND1 signaling

Y Subramaniam, B Sharma, A Aggarwal, DA Raja… - bioRxiv, 2023 - biorxiv.org
Vertebrate pigmentation is an outcome of an interplay of several signaling pathways that result
in immense diversity of pigment patterns observed across the animal kingdom. Transitory …

kinesin recruitment by adapter SKIP on melanosomes is dynamically controlled by LC3B phosphorylation

Y Subramaniam, D Murthy, DA Raja, A Ramkumar… - BioRxiv, 2021 - biorxiv.org
Anterograde melanosome transport is essential for adaptive skin tanning response. However,
the molecular components involved, their interplay and regulation by external cues in …

Reverse Genetic Approach to Identify Regulators of Pigmentation using Zebrafish

B Sharma, YJ Subramaniam, DA Raja… - JoVE (Journal of …, 2022 - jove.com
Melanocytes are specialized neural crest-derived cells present in the epidermal skin. These
cells synthesize melanin pigment that protects the genome from harmful ultraviolet radiations…

Histone code dictates fate biasing of neural crest cells to melanocyte lineage

DA Raja, Y Subramaniam, V Gotherwal, J Tanwar… - bioRxiv, 2019 - biorxiv.org
In the neural crest lineage, progressive fate-restriction and stem cell assignment are critical
for both development and regeneration. While the fate-commitment events have distinct …

pH controlled histone acetylation amplifies melanocyte differentiation program downstream of MITF

DA Raja, V Gotherwal, YJ Subramaniam, F Sultan… - bioRxiv, 2019 - biorxiv.org
Tanning response and melanocyte differentiation are mediated by the central transcription
factor MITF. Enigmatically, these involve rapid and selective induction of melanocyte …

pH-controlled histone acetylation amplifies melanocyte differentiation downstream of MITF

…, DA Raja, V Gotherwal, SA Burse, YJ Subramaniam… - 2020 - 202.54.249.144
Tanning response and melanocyte differentiation are mediated by the central transcription
factor MITF. This involves the rapid and selective induction of melanocyte maturation genes, …

The deal with DEAL for open access: The recent publish‐and‐read deals have increased momentum for open‐access publishing but may not solve the challenge of …

P Hunter - EMBO reports, 2020 - embopress.org
The move towards open-access publishing in the life sciences has gained momentum after
several major deals between publishers and institutions around the world, but it has also …