User profiles for Yoichi Sakata

Yoichi Sakata

Professor of Plant Genetics, Tokyo University of Agriculture
Verified email at nodai.ac.jp
Cited by 3113

Severe secondary deficiency of von Willebrand factor–cleaving protease (ADAMTS13) in patients with sepsis-induced disseminated intravascular coagulation: its …

…, A Ishiwata, K Takano, T Ohmori, Y Sakata - Blood, 2006 - ashpublications.org
Deficiency of ADAMTS13 is found in patients with thrombotic thrombocytopenic purpura (TTP),
and the genetic defects in the ADAMTS13 gene or the autoantibody against ADAMTS13 …

Significance of Cross-Linking of α2-Plasmin Inhibitor to Fibrin in Inhibition of Fibrinolysis and in Hemostasis

Y Sakata, N Aoki - The Journal of clinical investigation, 1982 - Am Soc Clin Investig
When blood is clotted, α 2 -plasmin inhibitor (α 2 PI) is cross-linked to fibrin by activated
fibrin-stabilizing factor (activated coagulation Factor XIII, plasma transglutaminase). The amount …

Essential Roles of Sphingosine 1-Phosphate/S1P1 Receptor Axis in the Migration of Neural Stem Cells Toward a Site of Spinal Cord Injury

…, E Kobayashi, Y Hoshino, Y Yatomi, Y Sakata - Stem …, 2007 - academic.oup.com
Neural stem/progenitor cells (NSPCs) migrate toward a damaged area of the central
nervous system (CNS) for the purpose of limiting and/or repairing the damage. Although this …

Tuning water-use efficiency and drought tolerance in wheat using abscisic acid receptors

…, JS Kim, Y Tsuboi, K Tanaka, H Kobayashi, Y Sakata… - Nature plants, 2019 - nature.com
Water availability is a key determinant of terrestrial plant productivity. Many climate models
predict that water stress will increasingly challenge agricultural yields and exacerbate …

Arabinogalactan Proteins Are Required for Apical Cell Extension in the Moss Physcomitrella patens

KJD Lee, Y Sakata, SL Mau, F Pettolino, A Bacic… - The Plant …, 2005 - academic.oup.com
Cell biological, structural, and genetic approaches have demonstrated the presence of
arabinogalactan proteins (AGPs) in the moss Physcomitrella patens and provided evidence for …

[PDF][PDF] Il2rg gene-targeted severe combined immunodeficiency pigs

…, J Mimuro, Y Kashiwakura, S Madoiwa, Y Sakata… - Cell stem cell, 2012 - cell.com
A porcine model of severe combined immunodeficiency (SCID) promises to facilitate human
cancer studies, the humanization of tissue for xenotransplantation, and the evaluation of …

[HTML][HTML] CRISPR/Cas9-mediated genome editing via postnatal administration of AAV vector cures haemophilia B mice

T Ohmori, Y Nagao, H Mizukami, A Sakata… - Scientific reports, 2017 - nature.com
Haemophilia B, a congenital haemorrhagic disease caused by mutations in coagulation factor
IX gene (F9), is considered an appropriate target for genome editing technology. Here, we …

Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity.

Y Sakata, S Curriden, D Lawrence… - Proceedings of the …, 1985 - National Acad Sciences
The effects of bovine activated protein C (APC) on the fibrinolytic activity of cultured bovine
aortic endothelial cells were investigated. Confluent monolayers were incubated with purified …

Plasminogen activator inhibitor 1 promotes a poor prognosis in sepsis-induced disseminated intravascular coagulation

…, Y Shintani, T Ohmori, J Mimuro, Y Sakata - International journal of …, 2006 - Springer
Sepsis-induced disseminated intravascular coagulation (DIC) is a serious condition
because it is closely linked to the development of multiple organ dysfunctions.We compared …

Plant Raf-like kinase integrates abscisic acid and hyperosmotic stress signaling upstream of SNF1-related protein kinase2

…, H Yoshikawa, T Umezawa, Y Sakata… - Proceedings of the …, 2015 - National Acad Sciences
Plant response to drought and hyperosmosis is mediated by the phytohormone abscisic
acid (ABA), a sesquiterpene compound widely distributed in various embryophyte groups. …