MITA/STING: a central and multifaceted mediator in innate immune response

Y Ran, HB Shu, YY Wang - Cytokine & growth factor reviews, 2014 - Elsevier
The recognition of nucleic acids is a general strategy used by the host to detect invading
pathogens. Many studies have established that MITA/STING is a central component in the …

Chemical and structural properties of dissolved black carbon released from biochars

X Qu, H Fu, J Mao, Y Ran, D Zhang, D Zhu - Carbon, 2016 - Elsevier
Black carbon (BC) has drawn wide interest due to its important role in the global carbon
budget and pollutant sequestration. Its soluble carbonaceous component, dissolved BC, is the …

Concentration levels, compositional profiles, and gas-particle partitioning of polybrominated diphenyl ethers in the atmosphere of an urban city in South China

…, XH Bi, SJ Chen, XM Wang, Y Ran… - … science & technology, 2006 - ACS Publications
Air samples were collected in June of 2004 from four sites in the city of Guangzhou, a typical
urban center in South China, to determine the levels, compositional profiles, and gas-…

Polybrominated diphenyl ethers in watershed soils of the Pearl River Delta, China: occurrence, inventory, and fate

MY Zou, Y Ran, J Gong, BX Mai… - Environmental science & …, 2007 - ACS Publications
Soils play an important role in the distribution and biogeochemical cycling of polybrominated
diphenyl ethers (PBDEs) as they are a major reservoir and sink for PBDEs due to their …

Contents and sources of polycyclic aromatic hydrocarbons and organochlorine pesticides in vegetable soils of Guangzhou, China

L Chen, Y Ran, B Xing, B Mai, J He, X Wei, J Fu… - Chemosphere, 2005 - Elsevier
We investigated contents, distribution and possible sources of PAHs and organochlorine
pesticides (Ops) in 43 surface and subsurface soils around the urban Guangzhou where …

ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response

…, C Li, P Xue, B Zhong, AP Mao, Y Ran… - Proceedings of the …, 2009 - National Acad Sciences
IFN-stimulated gene 56 (ISG56) is one of the first identified proteins induced by viruses and
type I IFNs. In this study, we identified ISG56 as a virus-induced protein associated with MITA…

[HTML][HTML] Regulation of virus-triggered signaling by OTUB1-and OTUB2-mediated deubiquitination of TRAF3 and TRAF6

…, AP Mao, B Zhong, Y Li, Y Liu, Y Gao, Y Ran… - Journal of Biological …, 2010 - ASBMB
Ubiquitination and deubiquitination have emerged as critical post-translational regulatory
mechanisms for activation or attenuation of the virus-triggered type I interferon (IFN) 2 2The …

Tripartite motif 8 (TRIM8) modulates TNFα-and IL-1β–triggered NF-κB activation by targeting TAK1 for K63-linked polyubiquitination

Q Li, J Yan, AP Mao, C Li, Y Ran… - Proceedings of the …, 2011 - National Acad Sciences
The tripartite motif (TRIM)-containing proteins are a family of proteins that have been known
to be involved in divergent biological processes, including important roles in immune …

Strong sorption of phenanthrene by condensed organic matter in soils and sediments

Y Ran, K Sun, Y Yang, B Xing… - Environmental Science & …, 2007 - ACS Publications
The nonhydrolyzable carbon (NHC) and black carbon (BC) in three contaminated soils and
seven sediments from the Pearl River Delta and Estuary, China, were isolated upon …

γ‐Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct

Y Ran, F Hossain, A Pannuti, CB Lessard… - EMBO molecular …, 2017 - embopress.org
γ‐Secretase inhibitors ( GSI s) are being actively repurposed as cancer therapeutics based
on the premise that inhibition of NOTCH 1 signaling in select cancers is therapeutic. Using …