Claudin‐14 regulates renal Ca++ transport in response to CaSR signalling via a novel microRNA pathway

Y Gong, V Renigunta, N Himmerkus, J Zhang… - The EMBO …, 2012 - embopress.org
The paracellular claudin channel of the thick ascending limb (TAL) of Henle is critical for Ca
++ reabsorption in the kidney. Genome‐wide association studies (GWASs) have identified …

Claudin-14 underlies Ca++-sensing receptor–mediated Ca++ metabolism via NFAT-microRNA–based mechanisms

Y Gong, J Hou - Journal of the American Society of Nephrology, 2014 - journals.lww.com
Pathologic dysregulation of extracellular calcium metabolism is difficult to correct. The
extracellular Ca++-sensing receptor (CaSR), a G protein–coupled receptor that regulates renal …

Mechanical properties of nanodiamond-reinforced hydroxyapatite composite coatings deposited by suspension plasma spraying

X Chen, B Zhang, Y Gong, P Zhou, H Li - Applied Surface Science, 2018 - Elsevier
Hydroxyapatite (HA) coatings suffer from poor mechanical properties, which can be
enhanced via incorporation of secondary bioinert reinforcement material. Nanodiamond (ND) …

Claudins in barrier and transport function—the kidney

Y Gong, J Hou - Pflügers Archiv-European Journal of Physiology, 2017 - Springer
Claudins are discovered to be key players in renal epithelial physiology. They are involved
in developmental, physiological, and pathophysiological differentiation. In the glomerular …

Virus entry and replication in the brain precedes blood-brain barrier disruption during intranasal alphavirus infection

MD Cain, H Salimi, Y Gong, L Yang… - Journal of …, 2017 - Elsevier
Viral infections of the central nervous system (CNS) are often associated with blood-brain
barrier (BBB) disruption, yet the impact of virus replication and immune cell recruitment on BBB …

Construction of mechanically durable superhydrophobic surfaces by thermal spray deposition and further surface modification

X Chen, Y Gong, X Suo, J Huang, Y Liu, H Li - Applied Surface Science, 2015 - Elsevier
Here we report a simple and cost-effective technical route for constructing superhydrophobic
surfaces with excellent abrasion resistance on various substrates. Rough surface structures …

Developing polyimide-copper antifouling coatings with capsule structures for sustainable release of copper

Y Liu, X Suo, Z Wang, Y Gong, X Wang, H Li - Materials & Design, 2017 - Elsevier
Polyimide-copper layers consisting of individual capsule-like splats were one-step fabricated
by solution precursor flame spray through controlling the reaction between dianhydride …

Epigenetic regulation of microRNAs controlling CLDN14 expression as a mechanism for renal calcium handling

Y Gong, N Himmerkus, A Plain, M Bleich… - Journal of the American …, 2015 - journals.lww.com
The kidney has a major role in extracellular calcium homeostasis. Multiple genetic linkage
and association studies identified three tight junction genes from the kidney—claudin-14,-16, …

The Cap1–claudin-4 regulatory pathway is important for renal chloride reabsorption and blood pressure regulation

Y Gong, M Yu, J Yang, E Gonzales… - Proceedings of the …, 2014 - National Acad Sciences
The paracellular pathway through the tight junction provides an important route for
transepithelial chloride reabsorption in the kidney, which regulates extracellular salt content and …

[HTML][HTML] In-situ SEM observations of ultrasonic cavitation erosion behavior of HVOF-sprayed coatings

H Zhang, X Chen, Y Gong, Y Tian, A McDonald… - Ultrasonics …, 2020 - Elsevier
Several typical high-velocity oxy-fuel (HVOF)-sprayed coatings, including WC-10Co4Cr
coatings, Co-based coatings, WC-10Co4Cr/Co-based composite coatings, and Fe-based …