User profiles for Yoshiaki Ito
 | Yoshiaki ItoProfessor, Cancer Science Institute of Singapore, NUS Verified email at nus.edu.sg Cited by 45848 |
[HTML][HTML] Causal relationship between the loss of RUNX3 expression and gastric cancer
QL Li, K Ito, C Sakakura, H Fukamachi, K Inoue, XZ Chi… - Cell, 2002 - cell.com
Runx3/Pebp2αC null mouse gastric mucosa exhibits hyperplasias due to stimulated
proliferation and suppressed apoptosis in epithelial cells, and the cells are resistant to growth-…
proliferation and suppressed apoptosis in epithelial cells, and the cells are resistant to growth-…
[HTML][HTML] Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
T lymphocytes differentiate in discrete stages within the thymus. Immature thymocytes lacking
CD4 and CD8 coreceptors differentiate into double-positive cells (CD4 + CD8 + ), which …
CD4 and CD8 coreceptors differentiate into double-positive cells (CD4 + CD8 + ), which …
[HTML][HTML] TAZ: a novel transcriptional co‐activator regulated by interactions with 14‐3‐3 and PDZ domain proteins
…, M Donowitz, A Hisaminato, T Fujiwara, Y Ito… - The EMBO …, 2000 - embopress.org
The highly conserved and ubiquitously expressed 14‐3‐3 proteins regulate differentiation,
cell cycle progression and apoptosis by binding intracellular phosphoproteins involved in …
cell cycle progression and apoptosis by binding intracellular phosphoproteins involved in …
Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog
…, H Yamamoto, T Fujita, T Furuichi, K Ito… - Genes & …, 2004 - genesdev.cshlp.org
The differentiation of mesenchymal cells into chondrocytes and chondrocyte proliferation
and maturation are fundamental steps in skeletal development. Runx2 is essential for …
and maturation are fundamental steps in skeletal development. Runx2 is essential for …
PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene.
…, JIE Lu, M Satake, K Shigesada, Y Ito - Proceedings of the …, 1993 - National Acad Sciences
cDNAs representing the alpha subunit of polyomavirus enhancer binding protein 2 (PEBP2;
also called PEA2) were isolated. The products of the cDNAs are highly homologous to that …
also called PEA2) were isolated. The products of the cDNAs are highly homologous to that …
MicroRNA-140 plays dual roles in both cartilage development and homeostasis
Osteoarthritis (OA), the most prevalent aging-related joint disease, is characterized by insufficient
extracellular matrix synthesis and articular cartilage degradation, mediated by several …
extracellular matrix synthesis and articular cartilage degradation, mediated by several …
[HTML][HTML] A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator
A protein module called the WW domain recognizes and binds to a short oligopeptide called
the PY motif, PPxY, to mediate protein–protein interactions. The PY motif is present in the …
the PY motif, PPxY, to mediate protein–protein interactions. The PY motif is present in the …
[HTML][HTML] A role for hematopoietic stem cells in promoting angiogenesis
…, T Watanabe, S Suenobu, Y Yamada, T Noda, Y Ito… - Cell, 2000 - cell.com
Angiogenesis is an important event for embryonic organogenesis as well as for tissue repair
in the adult. Here, we show that hematopoietic stem cells (HSCs) play important roles for …
in the adult. Here, we show that hematopoietic stem cells (HSCs) play important roles for …
Molecular cloning and characterization of PEBP2β, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2α
…, M Maruyama, M Satake, M Naito-Fujimoto, Y Ito… - Virology, 1993 - Elsevier
Polyomavirus enhancer binding protein, PEBP2 (PEA2), is a heterodimer of two distinct
subunits, α and β, of which the former directly binds to DNA and the latter acts auxiliary to …
subunits, α and β, of which the former directly binds to DNA and the latter acts auxiliary to …
[HTML][HTML] Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer
A Kamiya, T Kinoshita, Y Ito, T Matsui… - The EMBO …, 1999 - embopress.org
Fetal liver, the major site of hematopoiesis during embryonic development, acquires
additional various metabolic functions near birth. Although liver development has been …
additional various metabolic functions near birth. Although liver development has been …