User profiles for Yoshikazu Ohya
 | Yoshikazu OhyaProfessor of Genetics, University of Tokyo Verified email at edu.ku-tokyo.ac.jp Cited by 13150 |
Identification of yeast Rho1p GTPase as a regulatory subunit of 1, 3-β-glucan synthase
1,3-β-D-Glucan synthase [also known as β(1→3)glucan synthase] is a multi-enzyme complex
that catalyzes the synthesis of 1,3-β-linked glucan, a major structural component of the …
that catalyzes the synthesis of 1,3-β-linked glucan, a major structural component of the …
[HTML][HTML] Phosphatidylinositol-4-phosphate 5-kinase localized on the plasma membrane is essential for yeast cell morphogenesis
…, H Qadota, Y Anraku, Y Kanaho, Y Ohya - Journal of Biological …, 1998 - ASBMB
Phosphatidylinositol 4,5-biphosphate (PtdIns(4,5)P 2 ), an important element in eukaryotic
signal transduction, is synthesized either by phosphatidylinositol-4-phosphate 5-kinase (…
signal transduction, is synthesized either by phosphatidylinositol-4-phosphate 5-kinase (…
A global genetic interaction network maps a wiring diagram of cellular function
INTRODUCTION Genetic interactions occur when mutations in two or more genes combine
to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic …
to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic …
[HTML][HTML] Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast
Discovering target and off-target effects of specific compounds is critical to drug discovery
and development. We generated a compendium of "chemical-genetic interaction" profiles by …
and development. We generated a compendium of "chemical-genetic interaction" profiles by …
High-dimensional and large-scale phenotyping of yeast mutants
One of the most powerful techniques for attributing functions to genes in uni- and multicellular
organisms is comprehensive analysis of mutant traits. In this study, systematic and …
organisms is comprehensive analysis of mutant traits. In this study, systematic and …
[HTML][HTML] Activation of Yeast Protein Kinase C by Rho1 GTPase (∗)
…, H Qadota, CP Python, Y Anraku, Y Ohya… - Journal of Biological …, 1996 - ASBMB
We have investigated the role of the essential Rho1 GTPase in cell integrity signaling in
budding yeast. Conditional rho1 mutants display a cell lysis defect that is similar to that of …
budding yeast. Conditional rho1 mutants display a cell lysis defect that is similar to that of …
[HTML][HTML] Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs: implications for the molecular …
Human mitochondrial (mt) tRNA Lys has a taurine-containing modified uridine, 5-taurinomethyl-2-thiouridine
(τm 5 s 2 U), at its anticodon wobble position. We previously found that the …
(τm 5 s 2 U), at its anticodon wobble position. We previously found that the …
Polo-like kinase Cdc5 controls the local activation of Rho1 to promote cytokinesis
The links between the cell cycle machinery and the cytoskeletal proteins controlling
cytokinesis are poorly understood. The small guanine nucleotide triphosphate (GTP)–binding …
cytokinesis are poorly understood. The small guanine nucleotide triphosphate (GTP)–binding …
[HTML][HTML] A novel gene, STT4, encodes a phosphatidylinositol 4-kinase in the PKC1 protein kinase pathway of Saccharomyces cerevisiae.
A staurosporine-sensitive mutation (stt1) in yeast has been found in the PKC1 gene that
encodes a protein kinase C homologue (Yoshida, S., Ikeda, E., Uno, I., and Mitsuzawa, H. (1992…
encodes a protein kinase C homologue (Yoshida, S., Ikeda, E., Uno, I., and Mitsuzawa, H. (1992…
Intelligent image-activated cell sorting 2.0
…, Y Hosokawa, M Inaba, A Nakagawa, Y Ohya… - Lab on a Chip, 2020 - pubs.rsc.org
The advent of intelligent image-activated cell sorting (iIACS) has enabled high-throughput
intelligent image-based sorting of single live cells from heterogeneous populations. iIACS is …
intelligent image-based sorting of single live cells from heterogeneous populations. iIACS is …