Protective effects of Pycnogenol® on carbon tetrachloride-induced hepatotoxicity in Sprague–Dawley rats

YS Yang, TH Ahn, JC Lee, CJ Moon, SH Kim… - Food and Chemical …, 2008 - Elsevier
Oxidative damage is implicated in the pathogenesis of various liver injuries. In the present
study the ability of Pycnogenol ® (PYC) as an antioxidant to protect against CCl 4 -induced …

Nasal and pulmonary toxicity of titanium dioxide nanoparticles in rats

S Kwon, YS Yang, HS Yang, J Lee, MS Kang… - Toxicological …, 2012 - Springer
In recent decades, titanium dioxide (TiO 2 ) nanoparticles have been used in various
applications, including paints, coatings, and food. However, data are lacking on the toxicological …

Ameliorative effects of pycnogenol® on carbon tetrachloride‐induced hepatic oxidative damage in rats

TH Ahn, YS Yang, JC Lee, CJ Moon… - … Journal Devoted to …, 2007 - Wiley Online Library
This study evaluated the putative antioxidant activity of Pycnogenol ® (PYC) against CCl 4 ‐induced
hepatic oxidative damage in Sprague‐Dawley rats. A single oral dose of CCl 4 (…

[HTML][HTML] SYNCRIP controls miR-137 and striatal learning in animal models of methamphetamine abstinence

…, S Ham, S Ahn, J Kim, DW Cho, S Lee, YS Yang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Abstinence from prolonged psychostimulant use prompts stimulant withdrawal syndrome.
Molecular adaptations within the dorsal striatum have been considered the main hallmark of …

[HTML][HTML] KDS2010, a newly developed reversible MAO-B inhibitor, as an effective therapeutic candidate for Parkinson's disease

…, H Lee, H An, HJ Kim, SJ Park, DW Cho, YS Yang… - …, 2021 - Elsevier
Monoamine oxidase-B (MAO-B) is a well-established therapeutic target for Parkinson's
disease (PD); however, previous clinical studies on currently available irreversible MAO-B …

Evaluation of toxicity to triclosan in rats following 28 days of exposure to aerosol inhalation

YS Yang, JT Kwon, I Shim, HM Kim, P Kim… - Regulatory Toxicology …, 2015 - Elsevier
The present study was conducted to investigate the potential subchronic toxicity of triclosan (TCS)
in rats following 28 days of exposure by repeated inhalation. Four groups of six rats of …

The immunopharmaceutical effects and mechanisms of herb medicine

…, SS Lin, PH Liao, SC Young, CC Yang - Cellular & molecular …, 2008 - nature.com
In recent years, studies on evaluation of the therapeutic and toxic activity of herbal medicinal
products became available and popular. The advances in modern biotechnology have led …

Activation of autophagy rescues amiodarone-induced apoptosis of lung epithelial cells and pulmonary toxicity in rats

…, S Oh, YJ Choi, SH Oh, YS Yang, MJ Yang… - toxicological …, 2013 - academic.oup.com
Amiodarone, bi-iodinated benzofuran derivative, is one of the most frequently prescribed
and efficacious antiarrhythmic drugs. Despite its low incidence, amiodarone-induced …

[HTML][HTML] Safety assessment and gastrointestinal retention of orally administered cerium oxide nanoparticles in rats

…, J Rho, SM Park, MS Choi, S Kim, MB Heo, YS Yang… - Scientific Reports, 2024 - nature.com
Cerium oxide nanoparticles (CeO 2 NPs, NM-212) are well-known for their catalytic properties
and antioxidant potential, and have many applications in various industries, drug delivery, …

[HTML][HTML] Differential cellular tropism of lentivirus and adeno-associated virus in the brain of cynomolgus monkey

H An, DW Cho, SE Lee, YS Yang, SC Han… - Experimental …, 2016 - ncbi.nlm.nih.gov
Many researchers are using viruses to deliver genes of interest into the brains of laboratory
animals. However, certain target brain cells are not easily infected by viruses. Moreover, the …