User profiles for Youwei Xu

Youwei Xu

Shanghai Institute of Materia Medica Chinese Academy of Sciences
Verified email at simm.ac.cn
Cited by 968

Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody

W Yin, Y Xu, P Xu, X Cao, C Wu, C Gu, X He, X Wang… - Science, 2022 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has
become the dominant infective strain. We report the structures of the Omicron spike trimer on …

Rhodium (III)-catalyzed chemodivergent annulations between N-methoxybenzamides and sulfoxonium ylides via C–H activation

Y Xu, G Zheng, X Yang, X Li - Chemical communications, 2018 - pubs.rsc.org
Chemodivergent and redox-neutral annulations between N-methoxybenzamides and
sulfoxonium ylides have been realized via Rh(III)-catalyzed C–H activation. The sulfoxonium ylide …

[HTML][HTML] Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA. 2 variant compared to BA. 1 and their possible mouse …

Y Xu, C Wu, X Cao, C Gu, H Liu, M Jiang, X Wang… - Cell research, 2022 - nature.com
The Omicron BA.2 variant has become a dominant infective strain worldwide. Receptor
binding studies show that the Omicron BA.2 spike trimer exhibits 11-fold and 2-fold higher …

Sulfoxonium ylides as a carbene precursor in Rh (III)-catalyzed C–H acylmethylation of arenes

Y Xu, X Zhou, G Zheng, X Li - Organic letters, 2017 - ACS Publications
Sulfoxonium ylides act as an efficient carbene precursor in rhodium(III)-catalyzed C–H
acylmethlyation of a variety of arenes assisted by different chelating groups, and both aryl- and …

Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins

Y Wang, W Liu, Y Xu, X He, Q Yuan, P Luo… - Nature Chemical …, 2023 - nature.com
The complement receptors C3aR and C5aR1, whose signaling is selectively activated by
anaphylatoxins C3a and C5a, are important regulators of both innate and adaptive immune …

Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia–reperfusion injury through suppression of apoptosis and inflammation

S Zhang, Y Qi, Y Xu, X Han, J Peng, K Liu… - Neurochemistry …, 2013 - Elsevier
The neuroprotective effect and mechanism of the flavonoid-rich extract (FRE) from Rosa
laevigata Michx fruit on cerebral ischemia–reperfusion (I/R) injury were investigated. The …

[HTML][HTML] Antimicrobial peptide based magnetic recognition elements and Au@ Ag-GO SERS tags with stable internal standards: a three in one biosensor for isolation …

K Yuan, Q Mei, X Guo, Y Xu, D Yang, BJ Sánchez… - Chemical …, 2018 - pubs.rsc.org
In this study, a new biosensor based on a sandwich structure has been developed for the
isolation and detection of multiple bacterial pathogens via magnetic separation and SERS tags…

Rhodium (III)-catalyzed annulative coupling between arenes and sulfoxonium ylides via C–H activation

G Zheng, M Tian, Y Xu, X Chen, X Li - Organic Chemistry Frontiers, 2018 - pubs.rsc.org
The Rh(III)-catalyzed annulative C–H functionalization of arenes with sulfoxonium ylides
has been realized. Arenes assisted by diverse nucleophilic directing groups are viable …

Rhodium (III)-catalyzed synthesis of naphthols via C–H activation of sulfoxonium ylides

Y Xu, X Yang, X Zhou, L Kong, X Li - Organic letters, 2017 - ACS Publications
Direct and efficient synthesis of 1-naphthols has been realized via Rh(III)-catalyzed C–H
activation of sulfoxonium ylides and subsequent annulation with alkynes, where the …

Dioscin ameliorates cerebral ischemia/reperfusion injury through the downregulation of TLR4 signaling via HMGB-1 inhibition

X Tao, X Sun, L Yin, XU Han, L Xu, Y Qi, Y Xu… - Free Radical Biology …, 2015 - Elsevier
We previously reported the promising effect of dioscin against hepatic ischemia/reperfusion (I/R)
injury, but its effect on cerebral I/R injury remains unknown. In this work, an in vitro …