User profiles for Yu-Chuan Wang

Yu-Chuan Wang

National Health Research Institutes
Verified email at nhri.edu.tw
Cited by 955

PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

…, JM Hsu, L Nie, Y Chen, YC Wang, C Liu, WJ Wang… - Nature cell …, 2020 - nature.com
Although pyroptosis is critical for macrophages against pathogen infection, its role and
mechanism in cancer cells remains unclear. PD-L1 has been detected in the nucleus, with …

Use of ultrasound pretreatment in drying of fruits: drying rates, quality attributes, and shelf life extension

…, M Zhang, J Nsor-atindana, YC Wang - Drying …, 2011 - Taylor & Francis
Evolving advanced pretreatment techniques such as application of ultrasound prior to fruit
drying have attracted significant research and development efforts due to the rising demand …

[HTML][HTML] Nucleotide binding by the widespread high-affinity cyclic di-GMP receptor MshEN domain

YC Wang, KH Chin, ZL Tu, J He, CJ Jones… - Nature …, 2016 - nature.com
C-di-GMP is a bacterial second messenger regulating various cellular functions. Many bacteria
contain c-di-GMP-metabolizing enzymes but lack known c-di-GMP receptors. Recently, …

Numerical simulation of unsteady cavitation flow in a centrifugal pump at off-design conditions

T Lei, ZB Shan, CS Liang… - Proceedings of the …, 2014 - journals.sagepub.com
Unsteady cavitation flows in a centrifugal pump operating under off-design conditions are
investigated by using a numerical framework combining the re-normalization group k–ɛ …

Effects of ultrasound and microwave pretreatments of apple before spouted bed drying on rate of dehydration and physical properties

KJ Mothibe, M Zhang, AS Mujumdar, YC Wang… - Drying …, 2014 - Taylor & Francis
Pretreatments of fruits before drying have been proposed as alternative way to improve the
quality of dried fruits and reduce drying time. In the present study, the effects of different …

[HTML][HTML] Structural basis of SARS-CoV-2 main protease inhibition by a broad-spectrum anti-coronaviral drug

YC Wang, WH Yang, CS Yang, MH Hou… - American journal of …, 2020 - ncbi.nlm.nih.gov
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) or 2019 novel coronavirus (2019-nCoV), took tens of …

[HTML][HTML] Tannic acid suppresses SARS-CoV-2 as a dual inhibitor of the viral main protease and the cellular TMPRSS2 protease

SC Wang, Y Chen, YC Wang, WJ Wang… - American journal of …, 2020 - ncbi.nlm.nih.gov
The cell surface protein TMPRSS2 (transmembrane protease serine 2) is an androgen-responsive
serine protease important for prostate cancer progression and therefore an attractive …

[HTML][HTML] Crystal structure and functional implication of bacterial STING

TP Ko, YC Wang, CS Yang, MH Hou, CJ Chen… - Nature …, 2022 - nature.com
Mammalian innate immune sensor STING (STimulator of INterferon Gene) was recently
found to originate from bacteria. During phage infection, bacterial STING sense c-di-GMP …

A novel high maltose-forming α-amylase from Rhizomucor miehei and its application in the food industry

Y Wang, H Hu, J Ma, Q Yan, H Liu, Z Jiang - Food chemistry, 2020 - Elsevier
A novel α-amylase gene (RmAmyA) from Rhizomucor miehei was cloned and expressed in
Pichia pastoris. RmAmyA showed 70% amino acid identity with the α-amylase from …

Obesity increases the risk of renal involvement in children with Henoch–Schönlein purpura

YL Zhao, ZJ Liu, XM Bai, YC Wang, GH Li… - European journal of …, 2015 - Springer
The main aim of this study was to evaluate the relationship between obesity and renal
involvement in children with Henoch–Schönlein purpura (HSP). A retrospective study of 141 …