User profiles for Yuanjia Tang
 | Tang YuanjiaRenji Hospital, Shanghai JiaoTong University School of Medicine Verified email at sibs.ac.cn Cited by 5854 |
MicroRNA‐146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins
Objective MicroRNA have recently been identified as regulators that modulate target gene
expression and are involved in shaping the immune response. This study was undertaken to …
expression and are involved in shaping the immune response. This study was undertaken to …
MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1
Systemic lupus erythematosus is a complex autoimmune disease caused by genetic and
epigenetic alterations. DNA methylation abnormalities play an important role in systemic lupus …
epigenetic alterations. DNA methylation abnormalities play an important role in systemic lupus …
The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α
Inflammatory cytokines such as interleukin-17 (IL-17) promote inflammatory autoimmune
diseases. Although several microRNAs (miRNAs) have been shown to regulate autoimmune …
diseases. Although several microRNAs (miRNAs) have been shown to regulate autoimmune …
miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells
The recent discovery of microRNAs (miRNAs) has revealed a new layer of gene expression
regulation, affecting the immune system. Here, we identify their roles in regulating human …
regulation, affecting the immune system. Here, we identify their roles in regulating human …
[HTML][HTML] A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus
…, H Cui, Y Zhang, N Hirankarn, X Qian, Y Tang… - PLoS …, 2011 - journals.plos.org
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with a strong genetic
predisposition, characterized by an upregulated type I interferon pathway. MicroRNAs are …
predisposition, characterized by an upregulated type I interferon pathway. MicroRNAs are …
Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a multisystem, autoimmune disease that predominantly
affects women. Previous findings that duplicated Toll-like receptor 7 (Tlr7) promotes lupus…
affects women. Previous findings that duplicated Toll-like receptor 7 (Tlr7) promotes lupus…
[HTML][HTML] Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups
Systemic lupus erythematosus (SLE), a worldwide autoimmune disease with high heritability,
shows differences in prevalence, severity and age of onset among different ancestral …
shows differences in prevalence, severity and age of onset among different ancestral …
MicroRNA‐125a contributes to elevated inflammatory chemokine RANTES levels via targeting KLF13 in systemic lupus erythematosus
Objective MicroRNA (miRNA) have received increasing attention as posttranscriptional
regulators that fine‐tune the homeostasis of the inflammatory response. This study aimed to …
regulators that fine‐tune the homeostasis of the inflammatory response. This study aimed to …
Identification of the long noncoding RNA NEAT1 as a novel inflammatory regulator acting through MAPK pathway in human lupus
Long noncoding RNAs (lncRNAs) have recently been identified to be tightly linked to
diverse human diseases. However, our knowledge of Systemic Lupus Erythematosus (SLE)-related …
diverse human diseases. However, our knowledge of Systemic Lupus Erythematosus (SLE)-related …
miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression
Although it is well established that embryonic stem (ES) cells have the potential to differentiate
into dopamine neurons, the molecular basis of this process, particularly the role of …
into dopamine neurons, the molecular basis of this process, particularly the role of …