Long-term dual-color tracking of genomic loci by modified sgRNAs of the CRISPR/Cas9 system

…, B Xue, J Qin, C Sun, Y Sun, W Wei, Y Sun - Nucleic acids …, 2016 - academic.oup.com
Visualization of chromosomal dynamics is important for understanding many fundamental
intra-nuclear processes. Efficient and reliable live-cell multicolor labeling of chromosomal loci …

Architectural proteins for the formation and maintenance of the 3D genome

M Li, J Gan, Y Sun, Z Xu, J Yang, Y Sun, C Li - Science China Life …, 2020 - Springer
Eukaryotic genomes are densely packaged into hierarchical three-dimensional (3D) structures
that contain information about gene regulation and many other biological processes. With …

Multiplexed sgRNA expression allows versatile single nonrepetitive DNA labeling and endogenous gene regulation

…, L Chang, Y Sun, Y Hou, X Fan, Y Sun - ACS Synthetic …, 2018 - ACS Publications
The CRISPR/Cas9 system has made significant contributions to genome editing, gene
regulation and chromatin studies in recent years. High-throughput and systematic investigations …

[HTML][HTML] RAD21 is the core subunit of the cohesin complex involved in directing genome organization

Y Sun, X Xu, W Zhao, Y Zhang, K Chen, Y Li, X Wang… - Genome Biology, 2023 - Springer
Background The ring-shaped cohesin complex is an important factor for the formation of
chromatin loops and topologically associating domains (TADs) by loop extrusion. However, the …

[HTML][HTML] Mitochondrial localization signal of porcine circovirus type 2 capsid protein plays a critical role in cap-induced apoptosis

W Yu, Y Sun, Q He, C Sun, T Dong, L Zhang… - Veterinary …, 2021 - mdpi.com
Porcine circovirus 2 (PCV2), considered one of the most globally important porcine pathogens,
causes postweaning multisystemic wasting syndrome (PMWS). This virus is localized in …

[HTML][HTML] PN-ImTLSM facilitates high-throughput low background single-molecule localization microscopy deep in the cell

…, Y Sun, L Chang, S Shao, Y Li, M Zhang, C Sun… - Biophysics …, 2021 - ncbi.nlm.nih.gov
When imaging the nucleus structure of a cell, the out-of-focus fluorescence acts as background
and hinders the detection of weak signals. Light-sheet fluorescence microscopy (LSFM) …

Rational engineering and synthetic applications of a high specificity BiFC probe derived from Springgreen-M

Y Sun, Y Wang, K Chen, Y Sun, S Wang - Analyst, 2022 - pubs.rsc.org
As an indispensable genetically encoded optical method for detecting and visualizing
protein–protein interactions (PPIs) directly in live cells, bimolecular fluorescence complementation …

Curve aligning approach for gait authentication based on a wearable accelerometer

H Sun, T Yuao - Physiological measurement, 2012 - iopscience.iop.org
Gait authentication based on a wearable accelerometer is a novel biometric which can be
used for identity identification, medical rehabilitation and early detection of neurological …

Understanding Polyglutamine Diseases and Investigating the Functions of HSP90 and RPL36

Y Sun - International Journal of Biology and Life Sciences, 2023 - drpress.org
The expansion of CAG trinucleotide repeats has been considered to be highly related to the
polyglutamine disorders which effect the neuron and muscle system of organism. This study …

[HTML][HTML] A lightweight attention-based CNN model for efficient gait recognition with wearable IMU sensors

H Huang, P Zhou, Y Li, F Sun - Sensors, 2021 - mdpi.com
Wearable sensors-based gait recognition is an effective method to recognize people’s
identity by recognizing the unique way they walk. Recently, the adoption of deep learning …