Cellular communication can be mediated by the exchange of biological information, mainly
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …

Polycomb repressive complex 2 (PRC2) consists of three core subunits, EZH2, EED and
SUZ12, and plays pivotal roles in transcriptional regulation. The catalytic subunit EZH2 …

Background How exosomal microRNAs (miRNAs) derived from macrophages contribute to
the development of drug resistance in the context of the hypoxic tumor microenvironment in …

Epidemiologic studies associate consumption of genistein, in the form of dietary soy, with
lower rates of metastatic prostate cancer. We have previously shown that genistein inhibits …

Pneumocystis jirovecii is a major cause of life-threatening pneumonia in immunosuppressed
patients including transplant recipients and those with HIV/AIDS, yet surprisingly little is …

PGE 2 is a potent lipid mediator involved in maintaining homeostasis but also promotion of
acute inflammation or immune suppression in chronic inflammation and cancer. Nucleotide-…

Chemotherapy-induced premature ovarian failure (POF) in women is currently clinically
irreversible. Bone marrow mesenchymal stem cells (BMSCs) are a promising cellular …

Olfactomedin 4 (OLFM4) is a glycoprotein that has been found to be up-regulated in
inflammatory bowel diseases and Helicobacter pylori infected patients. However, its role in …

Multidrug resistance (MDR) remains a major obstacle to effective chemotherapy treatment in
ovarian cancer. In our study, paclitaxel‐resistant ovarian cancer patients and cell lines had …

Docosahexaenoic acid (DHA) is one of the major ingredients of fish oil and has been reported
to have anti‐inflammatory properties mediated through the GPR120 receptor. Whether …