This tutorial review provides recent developments in artificial cutters for site-selective scission
of DNA with the focus on chemistry-based DNA cutters. They are useful tools for molecular …

Conspectus Bacterial cytochrome P450s (P450s) are at the focus of attention as potential
biocatalysts for applications in green synthetic chemistry, as they possess high activity for the …

Cytochrome P450BM3 has long been regarded as a promising candidate for use as a
biocatalyst, owing to its excellent efficiency for the hydroxylation of unactivated C–H bonds. …

Nuclear import receptors (NIRs) not only transport RNA-binding proteins (RBPs) but also
modify phase transitions of RBPs by recognizing nuclear localization signals (NLSs). Toxic …

Biological methane oxidation is a highly desirable method for the conversion of natural gas
into a liquid to meet the increasing demand for fuel and chemical feedstock as well as …

The artificial restriction DNA cutter (ARCUT) method to cut double-stranded DNA at designated
sites has been developed. The strategy at the base of this approach, which does not rely …

Pseudo-complementary peptide nucleic acid (pcPNA) is a DNA analog in which modified
DNA bases 2,6-diaminopurine (D) and 2-thiouracil (U s ) 'decorate' a poly[N-(2-aminoethyl)…

Highly effective dipeptidic decoy molecules, which stimulate the direct hydroxylation of
benzene by wild-type cytochrome P450BM3, were successfully developed through a rationally …

The self-sufficient cytochrome P450 102A1 (P450BM3), known for its highly efficient activation
of molecular oxygen, was reconstituted with manganese protoporphyrin IX. This artificial …

Catching the structure of cytochrome P450 enzymes in flagrante is crucial for the development
of P450 biocatalysts, as most structures collected are found trapped in a precatalytic …