The number of new cases of pancreatic ductal adenocarcinoma is increasing with a cumulative
total of 495,773 cases worldwide, making it the fourteenth most common malignancy. …

Nuclear receptors (NR) collectively regulate several biological functions in various organs.
While NRs can be characterized by activation of the transcription of their signature genes, …

Endothelial glycocalyx coats healthy vascular endothelium and plays an important role in
vascular homeostasis. Although cerebral capillaries are categorized as continuous, as are …

Sex differences have been found in the pharmacokinetics of many drugs, and sex differences
of drugmetabolizing enzymes have been considered one of the major factors of this issue. …

Rat Sertoli cells phagocytose apoptotic spermatogenic cells, which consist mostly of spermatocytes,
in primary culture by recognizing phosphatidylserine (PS) exposed on the surface of …

Testicular Sertoli cells phagocytose apoptotic spermatogenic cells in a manner depending
on the membrane phospholipid phosphatidylserine (PS) expressed at the surface of the latter …

The effects of andrographolide, the major diterpenoid constituent of Andrographis paniculata,
on the expression of cytochrome P450 superfamily 1 members, including CYP1A1, …

Objectives Comprehensive genomic profiling (CGP) has been approved in Japan since
June 2019, enabling mutation‐specific therapy. Although tissue sampling via endoscopic …

Background There are limited studies on the results of comprehensive genomic profiling
testing for pancreatic cancer tissue specimens by endoscopic ultrasound-guided tissue …

In diabetes mellitus (DM) patients, the morbidity of infectious disease is increased, and these
infections can easily progress from local to systemic infection. Sepsis is a characteristic of …