We investigated the early development of the sea anemone Nematostella vectensis, an
emerging model system of the Cnidaria. Early cleavage stages are characterized by substantial …

The startling capacity of the amphibian Spemann organizer to induce naïve cells to form a
Siamese twin embryo with a second set of body axes is one of the hallmarks of developmental …

In animals, body axis patterning is based on the concentration-dependent interpretation of
graded morphogen signals, which enables correct positioning of the anatomical structures. …

The sea anemone Nematostella vectensis has recently been established as a new model
system for the understanding of the evolution of developmental processes. In particular, the …

Cnidarians are unique organisms in the animal kingdom because of their unequalled potential
to undergo reverse development (RD). The life cycle of some species can temporarily …

Functional and morphological planar cell polarity (PCP) oriented along the oral-aboral body
axis is clearly evident in the ectoderm of torpedo-shaped planula larvae of hydrozoan …

With the rapid increase of the quantity of molecular data, many animals joined the ranks of
the so‐called ‘emerging models’ of Evo‐Devo. One of the necessary steps in converting an …

In 1924 Hilde Mangold and Hans Spemann transplanted the dorsal blastopore lip of an
amphibian embryo to a host embryo's ventral side. This experiment revealed that the dorsal …

Robust morphogenetic events are pivotal for animal embryogenesis. However, comparison
of the modes of development of different members of a phylum suggests that the spectrum of …

Background In almost all metazoans examined to this respect, the axial patterning system
based on canonical Wnt (cWnt) signaling operates throughout the course of development. In …