Lung cancers caused by activating mutations in the epidermal growth factor receptor (EGFR)
are initially responsive to small molecule tyrosine kinase inhibitors (TKIs), but the efficacy of …

Highly active catalysts for the oxygen evolution reaction (OER) are required for the development
of photoelectrochemical devices that generate hydrogen efficiently from water using …

Mutations in the EGFR kinase are a cause of non-small-cell lung cancer. To understand their
mechanism of activation and effects on drug binding, we studied the kinetics of the L858R …

The clinical efficacy of epidermal growth factor receptor (EGFR) kinase inhibitors in EGFR-mutant
non-small-cell lung cancer (NSCLC) is limited by the development of drug-resistance …

The epidermal growth factor receptor (EGFR)-directed tyrosine kinase inhibitors (TKIs) gefitinib,
erlotinib and afatinib are approved treatments for non-small cell lung cancers harbouring …

Ni-(oxy)hydroxide-based materials are promising earth-abundant catalysts for electrochemical
water oxidation in basic media. Recent findings demonstrate that incorporation of trace Fe …

Colistin is the last resort for treatment of multidrug-resistant Acinetobacter baumannii.
Unfortunately, resistance to colistin has been reported all over the world. The highest resistance …

For platinum-based catalysts, the requirements for durability and activity are heightened by
the need to minimize platinum content, given its limited availability and high price. …

Epidermal growth factor receptor (EGFR) gene mutations (G719X, exon 19 deletions/insertions,
L858R, and L861Q) predict favorable responses to EGFR tyrosine kinase inhibitors (TKIs…

Porous structured silicon has been regarded as a promising candidate to overcome pulverization
of silicon-based anodes. However, poor mechanical strength of these porous particles …