admetSAR: a comprehensive source and free tool for assessment of chemical ADMET properties
Absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties play key roles
in the discovery/development of drugs, pesticides, food additives, consumer products, and …
in the discovery/development of drugs, pesticides, food additives, consumer products, and …
miRTarBase 2020: updates to the experimentally validated microRNA–target interaction database
MicroRNAs (miRNAs) are small non-coding RNAs (typically consisting of 18–25 nucleotides)
that negatively control expression of target genes at the post-transcriptional level. Owing to …
that negatively control expression of target genes at the post-transcriptional level. Owing to …
admetSAR 2.0: web-service for prediction and optimization of chemical ADMET properties
admetSAR was developed as a comprehensive source and free tool for the prediction of
chemical ADMET properties. Since its first release in 2012 containing 27 predictive models, …
chemical ADMET properties. Since its first release in 2012 containing 27 predictive models, …
[HTML][HTML] Prediction of drug-target interactions and drug repositioning via network-based inference
Drug-target interaction (DTI) is the basis of drug discovery and design. It is time consuming
and costly to determine DTI experimentally. Hence, it is necessary to develop computational …
and costly to determine DTI experimentally. Hence, it is necessary to develop computational …
Selective Induction of LTP and LTD by Postsynaptic [Ca2+]i Elevation
SN Yang, YG Tang, RS Zucker - Journal of …, 1999 - journals.physiology.org
Selective Induction of LTP and LTD by Postsynaptic [Ca 2+ ] i Elevation. Long-term potentiation
(LTP) and long-term depression (LTD), two prominent forms of synaptic plasticity at …
(LTP) and long-term depression (LTD), two prominent forms of synaptic plasticity at …
Nonepitaxial growth of hybrid core-shell nanostructures with large lattice mismatches
We report a synthetic route to achieving nanoscale heterostructures consisting of a metal
core and monocrystalline semiconductor shell with substantial lattice mismatches between …
core and monocrystalline semiconductor shell with substantial lattice mismatches between …
End-to-end structure-aware convolutional networks for knowledge base completion
Abstract Knowledge graph embedding has been an active research topic for knowledge base
completion, with progressive improvement from the initial TransE, TransH, DistMult et al to …
completion, with progressive improvement from the initial TransE, TransH, DistMult et al to …
[PDF][PDF] Mitochondrial involvement in post-tetanic potentiation of synaptic transmission
Y Tang, RS Zucker - Neuron, 1997 - cell.com
Posttetanic potentiation (PTP) is an essential aspect of synaptic transmission that arises from
a persistent presynaptic [Ca 2+ ] i following tetanic stimulation. At crayfish neuromuscular …
a persistent presynaptic [Ca 2+ ] i following tetanic stimulation. At crayfish neuromuscular …
[HTML][HTML] Identification of aneuploidy-selective antiproliferation compounds
YC Tang, BR Williams, JJ Siegel, A Amon - Cell, 2011 - cell.com
Aneuploidy, an incorrect chromosome number, is a hallmark of cancer. Compounds that cause
lethality in aneuploid, but not euploid, cells could therefore provide new cancer therapies. …
lethality in aneuploid, but not euploid, cells could therefore provide new cancer therapies. …
Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir
The complete genome sequence of Geobacillus thermodenitrificans NG80-2, a thermophilic
bacillus isolated from a deep oil reservoir in Northern China, consists of a 3,550,319-bp …
bacillus isolated from a deep oil reservoir in Northern China, consists of a 3,550,319-bp …