At presynaptic active zones, neurotransmitter release is initiated by the opening of voltage-gated
Ca 2+ channels close to docked vesicles. The mechanisms that enrich Ca 2+ channels …

Reconstructing axonal projections of single neurons at the whole-brain level is currently a
converging goal of the neuroscience community that is fundamental for understanding the …

Emerging evidence suggests that the nervous system is involved in tumor development in the
periphery, however, the role of the central nervous system remains largely unknown. Here, …

We have developed an open-source software called bi-channel image registration and deep-learning
segmentation (BIRDS) for the mapping and analysis of 3D microscopy data and …

Neocortical areas communicate through extensive axonal projections, but the logic of
information transfer remains poorly understood, because the projections of individual neurons …

Clinical observations indicate that the paramedian region of the thalamus is a critical node for
controlling wakefulness. However, the specific nucleus and neural circuitry for this function …

At eye opening, neurons in primary visual cortex (V1) are selective for stimulus features, but
circuits continue to refine in an experience-dependent manner for some weeks thereafter. …

The nucleus accumbens (NAc) is the ventral part of the striatum and the interface between
cognition, emotion, and action. It is composed of three major subnuclei: ie, NAc core (NAcC), …

Bone regeneration remains a great clinical challenge. Low intensity near-infrared (NIR) light
showed strong potential to promote tissue regeneration, offering a promising strategy for …

Recently, we have reported that dentate mossy cells (MCs) control memory precision via
directly and functionally innervating local somatostatin (SST) inhibitory interneurons. Here, we …