Endometriosis is a common complex inflammatory condition characterised by the presence
of endometrium-like tissue outside the uterus, mainly in the pelvic area. It is associated with …

Endometriosis is a common condition associated with debilitating pelvic pain and infertility.
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …

Purpose The aim of this study is to examine the impact of female body mass index (BMI) on
IVF cycle outcomes. Methods This is a retrospective cohort study including 51,198 women …

Advances in genomics are revolutionizing how diseases are prevented, diagnosed, and
treated, across all fields of medicine. In reproductive medicine, genomic technologies are used …

As IVF becomes an increasingly popular method for human reproduction, it is more critical
than ever to understand the unique molecular composition of the mammalian oocyte. DNA …

The mechanisms that mediate the establishment of totipotency during the egg-to-embryo
transition in mammals remain poorly understood. However, it is clear that unique factors stored …

Organelle positioning and movement in oocytes is largely mediated by microtubules (MTs)
and their associated motor proteins. While yet to be studied in germ cells, cargo trafficking in …

In an effort to better understand oocyte function, we utilized two‐dimensional (2D)
electrophoresis and mass spectrometry to identify proteins that are differentially expressed during …

During growth, mammalian oocytes accumulate and store tubulin that is required for oocyte
maturation and early embryonic cleavage. The mechanism underlying tubulin storage and …

During oocyte maturation, endoplasmic reticulum (ER) and mitochondria undergo a
dramatic re-localization that is important for calcium oscillations, calcium homeostasis, egg …