A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement
…, K Fragaki, L Berg-Alonso, Y Kageyama… - Brain, 2014 - academic.oup.com
Mitochondrial DNA instability disorders are responsible for a large clinical spectrum, among
which amyotrophic lateral sclerosis-like symptoms and frontotemporal dementia are …
which amyotrophic lateral sclerosis-like symptoms and frontotemporal dementia are …
Parkin‐independent mitophagy requires D rp1 and maintains the integrity of mammalian heart and brain
Y Kageyama, M Hoshijima, K Seo, D Bedja… - The EMBO …, 2014 - embopress.org
Mitochondrial dynamics and mitophagy have been linked to cardiovascular and neurodegenerative
diseases. Here, we demonstrate that the mitochondrial division dynamin D rp1 and …
diseases. Here, we demonstrate that the mitochondrial division dynamin D rp1 and …
[PDF][PDF] Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors
Mitochondrial division is essential for mitosis and metazoan development, but a mechanistic
role in cancer biology remains unknown. Here, we examine the direct effects of oncogenic …
role in cancer biology remains unknown. Here, we examine the direct effects of oncogenic …
Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage
Y Kageyama, Z Zhang, R Roda, M Fukaya… - Journal of Cell …, 2012 - rupress.org
Mitochondria divide and fuse continuously, and the balance between these two processes
regulates mitochondrial shape. Alterations in mitochondrial dynamics are associated with …
regulates mitochondrial shape. Alterations in mitochondrial dynamics are associated with …
Treatment of hypertensive cerebellar hemorrhage–surgical or conservative management?
S Kobayashi, A Sato, Y Kageyama, H Nakamura… - …, 1994 - journals.lww.com
ONE HUNDRED AND one consecutive patients with hypertensive cerebellar hemorrhage
were analyzed to determine the criteria for surgery. New criteria based on the patient's …
were analyzed to determine the criteria for surgery. New criteria based on the patient's …
CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis
…, F Burté, S Lacas‐Gervais, Y Kageyama… - EMBO molecular …, 2016 - embopress.org
CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired
mitochondrial genome maintenance and inhibition of apoptosis | EMBO Molecular Medicine All …
mitochondrial genome maintenance and inhibition of apoptosis | EMBO Molecular Medicine All …
Mitochondrial division: molecular machinery and physiological functions
Y Kageyama, Z Zhang, H Sesaki - Current opinion in cell biology, 2011 - Elsevier
Mitochondrial division has emerged as a key mechanism for this essential organelle to
maintain its structural integrity, intracellular distribution, and functional competence. An …
maintain its structural integrity, intracellular distribution, and functional competence. An …
Neuropathologic, genetic, and longitudinal cognitive profiles in primary age-related tauopathy (PART) and Alzheimer's disease
WR Bell, Y An, Y Kageyama, C English, GL Rudow… - Alzheimer's & …, 2019 - Elsevier
Introduction Primary age-related tauopathy (PART) is a recently described entity that can
cause cognitive impairment in the absence of Alzheimer's disease (AD). Here, we compared …
cause cognitive impairment in the absence of Alzheimer's disease (AD). Here, we compared …
Cryptic exon incorporation occurs in Alzheimer's brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43
…, W Bell, KD LaClair, JP Ling, H Han, Y Kageyama… - Acta …, 2017 - Springer
Abnormal accumulation of TDP-43 into cytoplasmic or nuclear inclusions with accompanying
nuclear clearance, a common pathology initially identified in amyotrophic lateral sclerosis (…
nuclear clearance, a common pathology initially identified in amyotrophic lateral sclerosis (…
[HTML][HTML] Diffeomorphic registration with intensity transformation and missing data: Application to 3D digital pathology of Alzheimer's disease
This paper examines the problem of diffeomorphic image registration in the presence of
differing image intensity profiles and sparsely sampled, missing, or damaged tissue. Our …
differing image intensity profiles and sparsely sampled, missing, or damaged tissue. Our …