Background: Spectral imaging extends the capabilities of biological and clinical studies to
simultaneously study multiple features such as organelles and proteins qualitatively and …

Single particle tracking is an essential tool in the study of complex systems and biophysics
and it is commonly analyzed by the time-averaged mean square displacement (MSD) of the …

Sleep is essential to all animals with a nervous system. Nevertheless, the core cellular function
of sleep is unknown, and there is no conserved molecular marker to define sleep across …

Measuring the mechanical properties of single-stranded DNA (ssDNA) is a challenge that has
been addressed by different methods lately. The short persistence length, fragile structure, …

Karyotype analysis by means of chromosome banding techniques is the pillar of cytogenetic
diagnostics, both in the clinical and in the cancer cytogenetic laboratory. Using …

For centuries, physical imaging tools have been opening new frontiers in biology. The
discovery of the cell nucleus by Scottish botanist Robert Brown was made possible by early-19th-…

We measured individual trajectories of fluorescently labeled telomeres in the nucleus of
eukaryotic cells in the time range of 10− 2–10 4 sec by combining a few acquisition methods. At …

A new design of dye-sensitized solar cells involves colloidal semiconductor quantum dots
that serve as antennas, funneling absorbed light to the charge separating dye molecules via …

Improving the spatial resolution of optical microscopes is important for a vast number of
applications in the life sciences. Optical microscopy allows intact samples and living cells to be …

We generated a system for in vivo visualization and analysis of mammalian mRNA transcriptional
kinetics of single alleles in real time, using single-gene integrations. We obtained high-…