User profiles for Yuya Kiguchi
yuya kiguchiDepartment of Computational Biology and Medical Sciences,
the University of Tokyo Verified email at edu.ku-tokyo.ac.jp Cited by 776 |
Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation
Intestinal colonization by bacteria of oral origin has been correlated with several negative
health outcomes, including inflammatory bowel disease. However, a causal role of oral …
health outcomes, including inflammatory bowel disease. However, a causal role of oral …
[HTML][HTML] Extensive gut virome variation and its associations with host and environmental factors in a population-level cohort
S Nishijima, N Nagata, Y Kiguchi, Y Kojima… - Nature …, 2022 - nature.com
Indigenous bacteriophage communities (virome) in the human gut have a huge impact on
the structure and function of gut bacterial communities (bacteriome), but virome variation at a …
the structure and function of gut bacterial communities (bacteriome), but virome variation at a …
Long-read metagenomics of multiple displacement amplified DNA of low-biomass human gut phageomes by SACRA pre-processing chimeric reads
The human gut bacteriophage community (phageome) plays an important role in the host’s
health and disease; however, the entire structure is poorly understood, partly owing to the …
health and disease; however, the entire structure is poorly understood, partly owing to the …
[HTML][HTML] Uncovering microbiomes of the rice phyllosphere using long-read metagenomic sequencing
S Masuda, P Gan, Y Kiguchi, M Anda, K Sasaki… - Communications …, 2024 - nature.com
The plant microbiome is crucial for plant growth, yet many important questions remain, such
as the identification of specific bacterial species in plants, their genetic content, and location …
as the identification of specific bacterial species in plants, their genetic content, and location …
[HTML][HTML] Recovery of microbial DNA by agar-containing solution from extremely low-biomass specimens including skin
R Kurokawa, H Masuoka, L Takayasu, Y Kiguchi… - Scientific Reports, 2023 - nature.com
Recovering a sufficient amount of microbial DNA from extremely low-biomass specimens,
such as human skin, to investigate the community structure of the microbiome remains …
such as human skin, to investigate the community structure of the microbiome remains …
Identification of the Set of Genes, Including Nonannotated morA, under the Direct Control of ModE in Escherichia coli
…, A Katayama, M Hiramatsu, Y Kiguchi… - Journal of …, 2013 - Am Soc Microbiol
ModE is the molybdate-sensing transcription regulator that controls the expression of genes
related to molybdate homeostasis in Escherichia coli . ModE is activated by binding …
related to molybdate homeostasis in Escherichia coli . ModE is activated by binding …
Uncovering plant microbiomes using long-read metagenomic sequencing
S Masuda, P Gan, Y Kiguchi, M Anda, K Sasaki… - bioRxiv, 2023 - biorxiv.org
The microbiome of plants plays a pivotal role in their growth and health. Despite its importance,
many fundamental questions about the microbiome remain largely unanswered, such as …
many fundamental questions about the microbiome remain largely unanswered, such as …
Horizontal gene transfer shapes pathogenic bacteria in multiple sclerosis
T Yamamura, D Takewaki, Y Kiguchi, H Masuoka… - 2023 - researchsquare.com
Multiple sclerosis (MS) is an autoimmune demyelinating disease influenced by environmental
factors. Except during relapses, baseline neurological status is generally stable in the …
factors. Except during relapses, baseline neurological status is generally stable in the …
Lifelong temporal dynamics of the gut microbiome associated with longevity in mice
…, T Umeyama, R Kurokawa, Y Ogata, Y Kiguchi… - bioRxiv, 2022 - biorxiv.org
The effect of lifelong dynamics on host longevity of the gut microbiome is largely unknown.
Herein, we analyzed the longitudinal fecal samples of seven sibling mice across their lifespan …
Herein, we analyzed the longitudinal fecal samples of seven sibling mice across their lifespan …
Impact of chimera-less long reads on metagenomics of human gut viromes treated with multiple displacement amplification
Background: The ecological and biological features of the indigenous phage community (virome)
in the human gut microbiome are poorly understood, possibly due to many fragmented …
in the human gut microbiome are poorly understood, possibly due to many fragmented …