User profiles for Yuyong Zhou

Yuyong Zhou

University of Copenhagen
Verified email at regionh.dk
Cited by 291

Nirmatrelvir-resistant SARS-CoV-2 variants with high fitness in an infectious cell culture system

Y Zhou, KA Gammeltoft, LA Ryberg, LV Pham… - Science …, 2022 - science.org
The oral protease inhibitor nirmatrelvir is of key importance for prevention of severe coronavirus
disease 2019 (COVID-19). To facilitate resistance monitoring, we studied severe acute …

[HTML][HTML] In vitro efficacy of artemisinin-based treatments against SARS-CoV-2

Y Zhou, K Gilmore, S Ramirez, E Settels… - Scientific Reports, 2021 - nature.com
Effective and affordable treatments for patients suffering from coronavirus disease 2019 (COVID-19),
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are …

Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 In Vitro

KA Gammeltoft, Y Zhou… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
Antivirals targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could
improve treatment of COVID-19. We evaluated the efficacy of clinically relevant hepatitis C …

[HTML][HTML] Efficacy of ion-channel inhibitors amantadine, memantine and rimantadine for the treatment of SARS-CoV-2 in vitro

Y Zhou, KA Gammeltoft, A Galli, A Offersgaard… - Viruses, 2021 - mdpi.com
We report the in vitro efficacy of ion-channel inhibitors amantadine, memantine and rimantadine
against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In VeroE6 cells…

Mutation of I176R in the E coding region weakens Japanese encephalitis virus neurovirulence, but not its growth rate in BHK-21 cells

Y Zhou, R Wu, Q Zhao, YF Chang, X Wen, Y Feng… - Archives of …, 2018 - Springer
Previously, we isolated the Japanese encephalitis virus (JEV) strain SCYA201201. In this
study, we passed the SCYA201201 strain in Syrian baby hamster kidney (BHK-21) cells 120 …

[HTML][HTML] Substitutions in SARS-CoV-2 Mpro Selected by Protease Inhibitor Boceprevir Confer Resistance to Nirmatrelvir

KA Gammeltoft, Y Zhou, LA Ryberg, LV Pham… - Viruses, 2023 - mdpi.com
Nirmatrelvir, which targets the SARS-CoV-2 main protease (Mpro), is the first-in-line drug for
prevention and treatment of severe COVID-19, and additional Mpro inhibitors are in …

Ecological landscape regulation approaches in Xilingol, Inner Mongolia: an urban ecosystem services perspective

M Zhang, Y Zhou, X Liu, Z Lu - International Journal of Sustainable …, 2017 - Taylor & Francis
Most cities or leagues in Inner Mongolia are the result of resource-based industrialization
processes and animal husbandry development, leading to a heterogeneous composition and …

The large sky area multi-object fiber spectroscopic telescope (LAMOST)

…, Y Zhang, M Zhao, F Zhou, GH Zhou… - … in Astronomy and …, 2012 - iopscience.iop.org
The Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST, also called the
Guo Shou Jing Telescope) is a special reflecting Schmidt telescope. LAMOST's special …

[HTML][HTML] Genomewide association study of leprosy

…, YP Sun, YL Cheng, HQ Tian, FS Zhou… - … England Journal of …, 2009 - Mass Medical Soc
Background The narrow host range of Mycobacterium leprae and the fact that it is refractory
to growth in culture has limited research on and the biologic understanding of leprosy. Host …

The first data release (DR1) of the LAMOST regular survey

…, ZC Zhang, M Zhao, F Zhou, X Zhou… - … in Astronomy and …, 2015 - iopscience.iop.org
The Large sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) general survey
is a spectroscopic survey that will eventually cover approximately half of the celestial sphere …