Narcolepsy with cataplexy is a disabling sleep disorder affecting 0·02% of adults worldwide.
It is characterised by severe, irresistible daytime sleepiness and sudden loss of muscle tone …

Rapid eye movement (REM) sleep behaviour disorder (RBD) is a parasomnia that is
characterized by loss of muscle atonia during REM sleep (known as REM sleep without atonia, or …

Objectives To provide evidence-based recommendations and guidance to the public
regarding indicators of good sleep quality across the life-span. Methods The National Sleep …

Background: Idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) is a
parasomnia that is an important risk factor for Parkinson's disease (PD) and Lewy body dementia. …

Idiopathic REM sleep behaviour disorder (iRBD) is a powerful early sign of Parkinson’s
disease, dementia with Lewy bodies, and multiple system atrophy. This provides an …

Narcolepsy is a rare brain disorder that reflects a selective loss or dysfunction of orexin (also
known as hypocretin) neurons of the lateral hypothalamus. Narcolepsy type 1 (NT1) is …

Importance and study objective The COVID-19 pandemic has produced unprecedented
changes in social, work, and leisure activities, which all have had major impact on sleep and …

Background Narcolepsy is characterised by excessive daytime sleepiness (EDS) and
cataplexy. Histamine neurons are crucial to maintain wakefulness. We assessed the safety and …

Restless legs syndrome (RLS) is a common sensorimotor disorder characterized by an urge
to move that appears during rest or is exacerbated by rest, that occurs in the evening or …

Objective To assess whether risk factors for Parkinson disease and dementia with Lewy
bodies increase rate of defined neurodegenerative disease in idiopathic rapid eye movement (…