Mycobacterium abscessus is a nontuberculous mycobacterial species, which has recently
emerged as responsible for a wide spectrum of clinical manifestations, including pulmonary …

Toxin-antitoxin (TA) systems regulate fundamental cellular processes in bacteria and
represent potential therapeutic targets. We report a new RES-Xre TA system in multiple human …

There is an unmet medical need for effective treatments against Mycobacterium abscessus
pulmonary infections, to which cystic fibrosis (CF) patients are particularly vulnerable. Recent …

Fifteen carbapenemase-producing Enterobacteriaceae isolates and 12 carbapenemase-producing
Pseudomonas aeruginosa isolates were recovered from patients hospitalized …

Pseudomonas aeruginosa can manipulate eukaryotic host cells using secreted effectors
delivered by the type III or the type VI Secretion Systems (T3SS and T6SS). The T3SS allows …

The human pathogen Mycobacterium tuberculosis requires a P 1B -ATPase metal exporter,
CtpC (Rv3270), for resistance to zinc poisoning. Here, we show that zinc resistance also …

Mycobacterium abscessus biofilm aggregates have been shown in the lungs of cystic fibrosis
patients and are often tolerant to drugs. Herein, we analyzed bi-dimensional images of …

Mycobacterium abscessus is a multi-drug-resistant non-tuberculous mycobacterial species
causing tuberculosis-like lung infections. The functional characterization of the extensive …

Mycobacterium abscessus (Mab) is an increasingly recognized pulmonary pathogen. How
Mab is internalized by macrophages and establishes infection remains unknown. Here, we …

Host metabolism reprogramming is a key feature of Mycobacterium tuberculosis (Mtb)
infection that enables the survival of this pathogen within phagocytic cells and modulates the …