User profiles for Yvonne Dombrowski
Yvonne DombrowskiQueen's University Belfast Verified email at qub.ac.uk Cited by 8935 |
[HTML][HTML] QuPath: Open source software for digital pathology image analysis
…, MB Loughrey, JA Fernández, Y Dombrowski… - Scientific reports, 2017 - nature.com
QuPath is new bioimage analysis software designed to meet the growing need for a user-friendly,
extensible, open-source solution for digital pathology and whole slide image analysis. …
extensible, open-source solution for digital pathology and whole slide image analysis. …
Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions
Y Dombrowski, M Peric, S Koglin… - Science translational …, 2011 - science.org
The proinflammatory cytokine interleukin-1β (IL-1β) plays a central role in the pathogenesis
and the course of inflammatory skin diseases, including psoriasis. Posttranscriptional …
and the course of inflammatory skin diseases, including psoriasis. Posttranscriptional …
[HTML][HTML] Oligodendrocytes in development, myelin generation and beyond
S Kuhn, L Gritti, D Crooks, Y Dombrowski - Cells, 2019 - mdpi.com
Oligodendrocytes are the myelinating cells of the central nervous system (CNS) that are
generated from oligodendrocyte progenitor cells (OPC). OPC are distributed throughout the …
generated from oligodendrocyte progenitor cells (OPC). OPC are distributed throughout the …
Regulatory T cells promote myelin regeneration in the central nervous system
Y Dombrowski, T O'hagan, M Dittmer, R Penalva… - Nature …, 2017 - nature.com
Regeneration of CNS myelin involves differentiation of oligodendrocytes from
oligodendrocyte progenitor cells. In multiple sclerosis, remyelination can fail despite abundant …
oligodendrocyte progenitor cells. In multiple sclerosis, remyelination can fail despite abundant …
Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL …
…, J Glas, J Diegelmann, S Koglin, Y Dombrowski… - Gut, 2014 - gut.bmj.com
Background We analysed incidence, predictors, histological features and specific treatment
options of anti-tumour necrosis factor α (TNF-α) antibody-induced psoriasiform skin lesions …
options of anti-tumour necrosis factor α (TNF-α) antibody-induced psoriasiform skin lesions …
GDF-15 contributes to proliferation and immune escape of malignant gliomas
…, I Tritschler, M Mittelbronn, Y Dombrowski… - Clinical cancer …, 2010 - AACR
Purpose: Growth and differentiation factor (GDF)-15 is a member of the transforming growth
factor (TGF)-β family. GDF-15 is necessary for the maintenance of pregnancy but has also …
factor (TGF)-β family. GDF-15 is necessary for the maintenance of pregnancy but has also …
Antimicrobial peptides and proinflammatory cytokines in periprosthetic joint infection
H Gollwitzer, Y Dombrowski, PM Prodinger, M Peric… - JBJS, 2013 - journals.lww.com
Background: Differentiation between septic and aseptic loosening of joint replacements is
essential for successful revision surgery, but reliable markers for the diagnosis of low-grade …
essential for successful revision surgery, but reliable markers for the diagnosis of low-grade …
Macrophage migration inhibitory factor contributes to the immune escape of ovarian cancer by down-regulating NKG2D
M Krockenberger, Y Dombrowski, C Weidler… - The Journal of …, 2008 - journals.aai.org
The proinflammatory cytokine macrophage migration inhibitory factor (MIF) stimulates tumor
cell proliferation, migration, and metastasis; promotes tumor angiogenesis; suppresses p53-…
cell proliferation, migration, and metastasis; promotes tumor angiogenesis; suppresses p53-…
[HTML][HTML] Vitamin D analogs differentially control antimicrobial peptide/“alarmin” expression in psoriasis
M Peric, S Koglin, Y Dombrowski, K Groß, E Bradac… - PloS one, 2009 - journals.plos.org
Antimicrobial peptides (AMPs) are strongly expressed in lesional skin in psoriasis and play
an important role as proinflammatory “alarmins” in this chronic skin disease. Vitamin D …
an important role as proinflammatory “alarmins” in this chronic skin disease. Vitamin D …
Aging impairs peritoneal but not bone marrow‐derived macrophage phagocytosis
E Linehan, Y Dombrowski, R Snoddy, PG Fallon… - Aging cell, 2014 - Wiley Online Library
Aging results in deterioration of the immune system, which is associated with increased
susceptibility to infection and impaired wound healing in the elderly. Phagocytosis is an …
susceptibility to infection and impaired wound healing in the elderly. Phagocytosis is an …