Deep-learning language models have shown promise in various biotechnological applications,
including protein design and engineering. Here we describe ProGen, a language model …

The breadth of genomic diversity found among organisms in nature allows populations to
adapt to diverse environments 1 , 2 . However, genomic diversity is difficult to generate in the …

… c) Crystal structure of BP showing the in-plane anisotropy between armchair (AC) and zigzag
(ZZ… Inset: E z -field distribution from computation. Reproduced with permission.93 Copyright …

The purpose of this study was to evaluate 10 process‐based terrestrial biosphere models that
were used for the IPCC fifth Assessment Report. The simulated gross primary productivity ( …

… Z-Scan measurements also showed that the oligomers with a moderate biradical character
(eg, 2Per-CN) showed higher TPA cross sections than those with large biradical characters (…

Cell-free systems that mimic essential cell functions, such as gene expression, have dramatically
expanded in recent years, both in terms of applications and widespread adoption. Here …

Ideal cell-free expression systems can theoretically emulate an in vivo cellular environment
in a controlled in vitro platform.1 This is useful for expressing proteins and genetic circuits in …

Accelerating the pace of synthetic biology experiments requires new approaches for rapid
prototyping of circuits from individual DNA regulatory elements. However, current testing …

10.7554/eLife.09771.001 While complex dynamic biological networks control gene
expression in all living organisms, the forward engineering of comparable synthetic networks …

This article is devoted to the study of high order difference methods for the fractional
diffusion-wave equation. The time fractional derivatives are described in the Caputo’s sense. A …