Peroxiredoxins (Prxs) are a ubiquitous family of antioxidant enzymes that also control
cytokine-induced peroxide levels which mediate signal transduction in mammalian cells. Prxs can …

Eukaryotic 2-Cys peroxiredoxins (2-Cys Prxs) not only act as antioxidants, but also appear
to regulate hydrogen peroxide–mediated signal transduction. We showthat bacterial 2-Cys …

2-Cys peroxiredoxins (Prxs) are a large and diverse family of peroxidases which, in addition
to their antioxidant functions, regulate cell signaling pathways, apoptosis, and differentiation…

Polymers (plastics) have transformed our lives by providing access to inexpensive and versatile
materials with a variety of useful properties. While polymers have improved our lives in …

Protein structures are dynamic and can explore a large conformational landscape 1 , 2 . Only
some of these structural substates are important for protein function (such as ligand binding…

Peroxiredoxins (Prxs) make up a ubiquitous class (proposed EC 1.11.1.15) of cysteine-dependent
peroxidases with roles in oxidant protection and signal transduction. An intriguing …

It has been suggested that the human species may be undergoing an evolutionary transition
in individuality (ETI). But there is disagreement about how to apply the ETI framework to our …

Escherichia coli pH 2.5 acid phosphatase gene (appA) and three mutants were expressed
in Pichia pastoris to assess the effect of strategic mutations or deletion on the enzyme (EcAP) …

A group of bacterial flavoproteins related to thioredoxin reductase contain an additional ≈
200‐amino‐acid domain including a redox‐active disulfide center at their N‐termini. These …

The integration of environmental DNA (eDNA) within management strategies for lotic
organisms requires translating eDNA detection and quantification data into inferences of the …