[HTML][HTML] Safety and immunogenicity of a hybrid-type vaccine booster in BBIBP-CorV recipients in a randomized phase 2 trial

…, S Hussein, MS ElDein, SS Yang, W Lei… - Nature …, 2022 - nature.com
NVSI-06-08 is a potential broad-spectrum recombinant COVID-19 vaccine that integrates
the antigens from multiple SARS-CoV-2 strains into a single immunogen. Here, we evaluate …

[HTML][HTML] Design of a mutation-integrated trimeric RBD with broad protection against SARS-CoV-2

…, FJ Shen, WM Zhou, K Xu, RQ Gao, F Tang, ZH Lei… - Cell Discovery, 2022 - nature.com
The continuous emergence of SARS-CoV-2 variants highlights the need of developing
vaccines with broad protection. Here, according to the immune-escape capability and …

A mosaic-type trimeric RBD-based COVID-19 vaccine candidate induces potent neutralization against Omicron and other SARS-CoV-2 variants

…, LF Du, S Shao, H Wang, JW Hou, K Xu, W Lei, ZH Lei… - Elife, 2022 - elifesciences.org
Large-scale populations in the world have been vaccinated with COVID-19 vaccines, however,
breakthrough infections of SARS-CoV-2 are still growing rapidly due to the emergence of …

Identification of key mutations responsible for the enhancement of receptor-binding affinity and immune escape of SARS-CoV-2 Omicron variant

WB Wang, YB Ma, ZH Lei, XF Zhang, J Li, SS Li… - Journal of Molecular …, 2023 - Elsevier
The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
raised concerns worldwide due to its enhanced transmissibility and immune escapability. …

[HTML][HTML] Laparoscopic or open liver resection for intrahepatic cholangiocarcinoma: A meta-analysis and systematic review

…, J Yang, Q Xie, J Gong, M Yang, T Mao, Z Lei - Frontiers in …, 2023 - frontiersin.org
Background: Although laparoscopic hepatectomy has been widely used in the treatment of
benign and malignant liver diseases, its applicability in intrahepatic cholangiocarcinoma (ICC…

[HTML][HTML] Design of hepadnavirus core protein-based chimeric virus-like particles carrying epitopes from respiratory syncytial virus

…, SS Yang, ZB Han, HL Wu, F Tang, XY Li, ZH Lei… - npj Vaccines, 2024 - nature.com
Respiratory syncytial virus (RSV) is one of the most important pathogens causing respiratory
tract infection in humans, especially in infants and the elderly. The identification and …

[HTML][HTML] Efficacy of lenvatinib combined with sequential transarterial chemoembolization for primary hepatocellular carcinoma and the effects on serum basic fibroblast …

…, KY Jiang, J Gong, X Zhao, BJ Gao, ZH Lei - Frontiers in …, 2022 - frontiersin.org
Objective: The aim of this research was to investigate the therapeutic efficacy of lenvatinib
combined with sequential transarterial chemoembolization (TACE) on primary hepatocellular …

[HTML][HTML] Safety and immunogenicity of a mosaic vaccine booster against Omicron and other SARS-CoV-2 variants: a randomized phase 2 trial

…, T Yang, S Hussein, MS ElDein, ZH Lei… - … and Targeted Therapy, 2023 - nature.com
An ongoing randomized, double-blind, controlled phase 2 trial was conducted to evaluate the
safety and immunogenicity of a mosaic-type recombinant vaccine candidate, named NVSI-…

[HTML][HTML] Analysis of risk factors for acute pancreatitis complicated with pancreatic sinistral portal hypertension and construction of predictive model

…, B Du, ZX Wang, JQ Fu, FW Gao, ZH Lei - Frontiers in …, 2024 - frontiersin.org
Objective: Pancreatic sinistral portal hypertension (PSPH) is a common complication of
acute pancreatitis (AP) and can cause massive gastrointestinal bleeding, which is one of the …

Exploring the Application of a Multi-Targeted Nursing Group for Enhanced Recovery After Surgery Using the LEER (“Less Pain”,“Early Movement”,“Early Return to a …

QY Xie, J Yang, ZH Lei, FW Gao, B Chen… - … Journal of General …, 2021 - Taylor & Francis
Objective To explore the effects and value of establishing a multi-target nursing group (MTNG)
for facilitating goal-oriented enhanced recovery after surgery (ERAS) using the LEER (“…