User profiles for Zeyad D. Nassar
Zeyad D NassarSchool of Medicine, University of Adelaide Verified email at adelaide.edu.au Cited by 1815 |
Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis
Fatty acid β-oxidation (FAO) is the main bioenergetic pathway in human prostate cancer (PCa)
and a promising novel therapeutic vulnerability. Here we demonstrate therapeutic efficacy …
and a promising novel therapeutic vulnerability. Here we demonstrate therapeutic efficacy …
[HTML][HTML] Correlation of antiangiogenic, antioxidant and cytotoxic activities of some Sudanese medicinal plants with phenolic and flavonoid contents
…, HM Baharetha, NS Muslim, ZD Nassar… - … and alternative medicine, 2014 - Springer
Background Consumption of medicinal plants to overcome diseases is traditionally belongs
to the characteristics of most cultures on this earth. Sudan has been a host and cradle to …
to the characteristics of most cultures on this earth. Sudan has been a host and cradle to …
Lipidomic profiling of clinical prostate cancer reveals targetable alterations in membrane lipid composition
…, T Gevaert, R Derua, E Waelkens, ZD Nassar… - Cancer research, 2021 - AACR
This study identifies malignancy and treatment-associated changes in lipid composition of
clinical prostate cancer tissues, suggesting that mediators of these lipidomic changes could …
clinical prostate cancer tissues, suggesting that mediators of these lipidomic changes could …
ELOVL5 is a critical and targetable fatty acid elongase in prostate cancer
… B–D, Phospholipidomic changes in total lipid abundance, abundance per lipid class, and
saturation in LNCaP cells following treatment with synthetic androgen mibolerone. Data, mean …
saturation in LNCaP cells following treatment with synthetic androgen mibolerone. Data, mean …
Extracellular fatty acids are the major contributor to lipid synthesis in prostate cancer
S Balaban, ZD Nassar, AY Zhang… - Molecular Cancer …, 2019 - AACR
Extracellular-derived FAs are primary building blocks for complex lipids and heterogeneity
in FA metabolism exists in prostate cancer that can influence tumor cell behavior. …
in FA metabolism exists in prostate cancer that can influence tumor cell behavior. …
Peri‐prostatic adipose tissue: the metabolic microenvironment of prostate cancer
Emerging data have linked certain features of clinical prostate cancer ( PC a) to obesity and,
more specifically, increased adiposity. Whereas the large number of clinical studies and …
more specifically, increased adiposity. Whereas the large number of clinical studies and …
[HTML][HTML] PTRF/Cavin-1 decreases prostate cancer angiogenesis and lymphangiogenesis
Caveolae are specialized plasma membrane subdomains implicated in cellular functions
such as migration, signalling and trafficking. Caveolin-1 and polymerase I and transcript …
such as migration, signalling and trafficking. Caveolin-1 and polymerase I and transcript …
Cat's whiskers tea (Orthosiphon stamineus) extract inhibits growth of colon tumor in nude mice and angiogenesis in endothelial cells via suppressing VEGFR …
MBK Ahamed, AFA Aisha, ZD Nassar… - Nutrition and …, 2012 - Taylor & Francis
Cat's whiskers (Orthosiphon stamineus) is commonly used as Java tea to treat kidney
stones including a variety of angiogenesis-dependent diseases such as tumorous edema, …
stones including a variety of angiogenesis-dependent diseases such as tumorous edema, …
[HTML][HTML] Diet-induced hypercholesterolemia promotes androgen-independent prostate cancer metastasis via IQGAP1 and caveolin-1
… The HC-D group showed higher bioluminescence intensity in the para-aortic lymph node
(p = 0.0007, Figure 1g), mesenteric lymph node (p = 0.0021, Figure 1h) and the lung (p = …
(p = 0.0007, Figure 1g), mesenteric lymph node (p = 0.0021, Figure 1h) and the lung (p = …
Activation of μ-opioid receptor and Toll-like receptor 4 by plasma from morphine-treated mice
In this study, we quantified the ability of opioids present in biological samples to activate the
μ-opioid receptor and TLR4 using cell-based assays. Each assay was standardised, in the …
μ-opioid receptor and TLR4 using cell-based assays. Each assay was standardised, in the …