[HTML][HTML] Rapid and ultrasensitive electromechanical detection of ions, biomolecules and SARS-CoV-2 RNA in unamplified samples

…, Y Wang, C Zhang, D Qu, C Fan, Y Xie, Z Zhu… - Nature Biomedical …, 2022 - nature.com
The detection of samples at ultralow concentrations (one to ten copies in 100 μl) in biofluids
is hampered by the orders-of-magnitude higher amounts of ‘background’ biomolecules. …

[PDF][PDF] Virus-host interactome and proteomic survey reveal potential virulence factors influencing SARS-CoV-2 pathogenesis

…, Y Yin, C Wang, Y Zhang, Z Zhu, Z Liu, C Peng, T Zhu… - Med, 2021 - cell.com
Background The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a global public health concern …

Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral …

…, W Guan, L Xu, Y Liu, S Wang, X Zhang, D Tian, Z Zhu… - The Lancet, 2013 - thelancet.com
Background On March 30, a novel influenza A subtype H7N9 virus (A/H7N9) was detected
in patients with severe respiratory disease in eastern China. Virological factors associated …

Early hypercytokinemia is associated with interferon-induced transmembrane protein-3 dysfunction and predictive of fatal H7N9 infection

…, L Li, M Zhou, S Yuan, J Sun, Z Zhu… - Proceedings of the …, 2014 - National Acad Sciences
A unique avian-origin A/H7N9 influenza virus has so far caused 134 cases with 44 deaths.
Probing the host factors contributing to disease severity, we found that lower levels of plasma …

[HTML][HTML] Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8+ T cells

Z Wang, Y Wan, C Qiu, S Quinones-Parra, Z Zhu… - Nature …, 2015 - nature.com
The avian origin A/H7N9 influenza virus causes high admission rates (>99%) and mortality (>30%),
with ultimately favourable outcomes ranging from rapid recovery to prolonged …

Risks and features of secondary infections in severe and critical ill COVID-19 patients

…, S Chen, F Sun, R Mao, C Qiu, Z Zhu… - Emerging microbes & …, 2020 - Taylor & Francis
Objectives Severe or critical COVID-19 is associated with intensive care unit admission,
increased secondary infection rate, and would lead to significant worsened prognosis. Risks …

Direct SARS-CoV-2 nucleic acid detection by Y-shaped DNA dual-probe transistor assay

…, W Liu, Y Wu, C Dai, Q Guo, D Qu, Z Zhu… - Journal of the …, 2021 - ACS Publications
Rapid screening of infected individuals from a large population is an effective means in
epidemiology, especially to contain outbreaks such as COVID-19. The gold standard assays for …

Ultrasensitive detection of SARS-CoV-2 antibody by graphene field-effect transistors

…, C Dai, R Chen, L Yang, Y Wu, T Ying, Z Zhu… - Nano Letters, 2021 - ACS Publications
The fast spread of SARS-CoV-2 has severely threatened the public health. Establishing a
sensitive method for SARS-CoV-2 detection is of great significance to contain the worldwide …

Pre-optimized phage therapy on secondary Acinetobacter baumannii infection in four critical COVID-19 patients

…, J Jin, T Li, L Shi, Q Wu, R Tan, M Zhu… - Emerging microbes & …, 2021 - Taylor & Francis
Phage therapy is recognized as a promising alternative to antibiotics in treating pulmonary
bacterial infections, however, its use has not been reported for treating secondary bacterial …

Ultraprecise antigen 10-in-1 pool testing by multiantibodies transistor assay

…, X Wang, Y Wu, H Kang, D Kong, Z Zhu… - Journal of the …, 2021 - ACS Publications
Effective screening of infectious diseases requires a fast, cheap, and population-scale testing.
Antigen pool testing can increase the test rate and shorten the screening time, thus being …