Multi-input RNAi-based logic circuit for identification of specific cancer cells

Z Xie, L Wroblewska, L Prochazka, R Weiss… - Science, 2011 - science.org
Engineered biological systems that integrate multi-input sensing, sophisticated information
processing, and precisely regulated actuation in living cells could be useful in a variety of …

[HTML][HTML] Non-invasive early detection of cancer four years before conventional diagnosis using a blood test

…, X Li, L Cheng, Z Zhang, H Niu, Z Li, Z Xie… - Nature …, 2020 - nature.com
Early detection has the potential to reduce cancer mortality, but an effective screening test
must demonstrate asymptomatic cancer detection years before conventional diagnosis in a …

[HTML][HTML] COVID-19 and healthcare system in China: challenges and progression for a sustainable future

S Sun, Z Xie, K Yu, B Jiang, S Zheng, X Pan - Globalization and Health, 2021 - Springer
With the ongoing COVID-19 outbreak, healthcare systems across the world have been pushed
to the brink. The approach of traditional healthcare systems to disaster preparedness and …

CRISPR transcriptional repression devices and layered circuits in mammalian cells

…, J Beal, MR Ebrahimkhani, J Huh, RN Hall, Z Xie… - Nature …, 2014 - nature.com
A key obstacle to creating sophisticated genetic circuits has been the lack of scalable device
libraries. Here we present a modular transcriptional repression architecture based on …

Organophosphorus flame retardants and plasticizers: sources, occurrence, toxicity and human exposure

GL Wei, DQ Li, MN Zhuo, YS Liao, ZY Xie, TL Guo… - Environmental …, 2015 - Elsevier
Due to the restricted use and ban of brominated flame retardants, organophosphorus compounds
(OPs), extensively used as flame retardants and plasticizers, are ubiquitous in various …

Annotations and Functional Analyses of the Rice WRKY Gene Superfamily Reveal Positive and Negative Regulators of Abscisic Acid Signaling in Aleurone Cells

Z Xie, ZL Zhang, X Zou, J Huang, P Ruas… - Plant …, 2005 - academic.oup.com
The WRKY proteins are a superfamily of regulators that control diverse developmental and
physiological processes. This family was believed to be plant specific until the recent …

[HTML][HTML] Cathepsin B in programmed cell death machinery: mechanisms of execution and regulatory pathways

Z Xie, M Zhao, C Yan, W Kong, F Lan… - Cell Death & …, 2023 - nature.com
Cathepsin B (CatB), a cysteine protease, is primarily localized within subcellular endosomal
and lysosomal compartments. It is involved in the turnover of intracellular and extracellular …

Interactions of two abscisic‐acid induced WRKY genes in repressing gibberellin signaling in aleurone cells

Z Xie, ZL Zhang, X Zou, G Yang, S Komatsu… - The Plant …, 2006 - Wiley Online Library
Gibberellins (GA) promote while abscisic acid (ABA) inhibits seed germination and post‐germination
growth. To address the cross‐talk of GA and ABA signaling, we studied two rice …

[HTML][HTML] Online risky behavior and sleep quality among Chinese college students: The chain mediating role of rumination and anxiety

WF Qiu, JP Ma, ZY Xie, XT Xie, CX Wang, YD Ye - Current psychology, 2023 - Springer
This study explored the chain mediating effects of rumination and anxiety in the relationship
between online risky behavior and sleep quality among Chinese college students. A sample …

Epigenetic regulation of antagonistic receptors confers rice blast resistance with yield balance

Y Deng, K Zhai, Z Xie, D Yang, X Zhu, J Liu, X Wang… - Science, 2017 - science.org
Crop breeding aims to balance disease resistance with yield; however, single resistance (R)
genes can lead to resistance breakdown, and R gene pyramiding may affect growth fitness. …