LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption
J Luo, Z Yang, YU Ma, Z Yue, H Lin, G Qu, J Huang… - Nature medicine, 2016 - nature.com
Tumor necrosis factor (TNF) superfamily member 11 (TNFSF11, also known as RANKL)
regulates multiple physiological or pathological functions, including osteoclast differentiation …
regulates multiple physiological or pathological functions, including osteoclast differentiation …
Efficient deep models for real-time 4k image super-resolution. NTIRE 2023 benchmark and report
This paper introduces a novel benchmark for efficient upscaling as part of the NTIRE 2023
Real-Time Image Super-Resolution (RTSR) Challenge, which aimed to upscale images from …
Real-Time Image Super-Resolution (RTSR) Challenge, which aimed to upscale images from …
[HTML][HTML] Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor α by inhibiting NF-κB signaling pathway
C Li, Z Yang, C Zhai, W Qiu, D Li, Z Yi, L Wang, J Tang… - Molecular cancer, 2010 - Springer
Background Tumor necrosis factor alpha (TNFα) has been used to treat certain tumors in
clinic trials. However, the curative effect of TNFα has been undermined by the induced-NF-κB …
clinic trials. However, the curative effect of TNFα has been undermined by the induced-NF-κB …
Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer
Tumor–stroma interactions contribute to tumorigenesis. Tumor cells can educate the stroma
at primary and distant sites to facilitate the recruitment of heterogeneous populations of …
at primary and distant sites to facilitate the recruitment of heterogeneous populations of …
Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy‐induced bone loss by regulating RANKL‐mediated NF‐κB and MAPK signaling pathways
Activation of NF‐κB and MAPK/activator protein 1 (AP‐1) signaling pathways by receptor
activator NF‐κB ligand (RANKL) is essential for osteoclast activity. Targeting NF‐κB and MAPK/…
activator NF‐κB ligand (RANKL) is essential for osteoclast activity. Targeting NF‐κB and MAPK/…
Efficient and accurate quantized image super-resolution on mobile NPUs, mobile AI & AIM 2022 challenge: report
Image super-resolution is a common task on mobile and IoT devices, where one often
needs to upscale and enhance low-resolution images and video frames. While numerous …
needs to upscale and enhance low-resolution images and video frames. While numerous …
Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF‐κB signaling pathway in colon cancer cells
Z Yang, C Li, X Wang, C Zhai, Z Yi… - Journal of cellular …, 2010 - Wiley Online Library
Dauricine, a bioactive component of Asiatic Moonseed Rhizome, has been widely used to
treat a large number of inflammatory diseases in traditional Chinese medicine. In our study, …
treat a large number of inflammatory diseases in traditional Chinese medicine. In our study, …
[HTML][HTML] RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis
Therapeutics targeting osteoclasts are commonly used treatments for bone metastasis;
however, whether and how osteoclasts regulate premetastatic niche and bone tropism are …
however, whether and how osteoclasts regulate premetastatic niche and bone tropism are …
Inhibition of breast cancer metastases by a novel inhibitor of TGFβ receptor 1
Background Transforming growth factor beta (TGFβ), which is implicated in metastasis to
various organs in breast cancer, is a potential target for new antitumor metastasis drugs. …
various organs in breast cancer, is a potential target for new antitumor metastasis drugs. …
Exact certification in global polynomial optimization via sums-of-squares of rational functions with rational coefficients
We present a hybrid symbolic-numeric algorithm for certifying a polynomial or rational
function with rational coefficients to be non-negative for all real values of the variables by …
function with rational coefficients to be non-negative for all real values of the variables by …