User profiles for Zhengqiao Zhao
Zhengqiao ZhaoPrinceton University Verified email at princeton.edu Cited by 595 |
[HTML][HTML] Critical assessment of metagenome interpretation: the second round of challenges
Evaluating metagenomic software is key for optimizing metagenome interpretation and focus
of the Initiative for the Critical Assessment of Metagenome Interpretation (CAMI). The CAMI …
of the Initiative for the Critical Assessment of Metagenome Interpretation (CAMI). The CAMI …
[HTML][HTML] Emerging priorities for microbiome research
…, A Sen Gupta, K Cheung, JG Powers, Z Zhao… - Frontiers in …, 2020 - frontiersin.org
Microbiome research has increased dramatically in recent years, driven by advances in
technology and significant reductions in the cost of analysis. Such research has unlocked a …
technology and significant reductions in the cost of analysis. Such research has unlocked a …
[HTML][HTML] Genetic grouping of SARS-CoV-2 coronavirus sequences using informative subtype markers for pandemic spread visualization
Z Zhao, BA Sokhansanj, C Malhotra… - PLoS computational …, 2020 - journals.plos.org
We propose an efficient framework for genetic subtyping of SARS-CoV-2, the novel coronavirus
that causes the COVID-19 pandemic. Efficient viral subtyping enables visualization and …
that causes the COVID-19 pandemic. Efficient viral subtyping enables visualization and …
[HTML][HTML] Amino Acid k-mer Feature Extraction for Quantitative Antimicrobial Resistance (AMR) Prediction by Machine Learning and Model Interpretation for Biological …
Simple Summary Infectious bacteria (microbes) are able to evolve to become resistant to
antibiotics (develop antimicrobial resistance, or AMR). Resistant microbes are harder to treat, …
antibiotics (develop antimicrobial resistance, or AMR). Resistant microbes are harder to treat, …
[HTML][HTML] 16S rRNA sequence embeddings: Meaningful numeric feature representations of nucleotide sequences that are convenient for downstream analyses
Advances in high-throughput sequencing have increased the availability of microbiome
sequencing data that can be exploited to characterize microbiome community structure in situ. …
sequencing data that can be exploited to characterize microbiome community structure in situ. …
[HTML][HTML] Interpretable and predictive deep neural network modeling of the SARS-Cov-2 spike protein sequence to predict COVID-19 disease severity
BA Sokhansanj, Z Zhao, GL Rosen - Biology, 2022 - mdpi.com
Simple Summary As COVID-19 shifts from pandemic to endemic, emerging variants may be
more or less virulent. Predicting whether an emerging COVID-19 variant has of high risk of …
more or less virulent. Predicting whether an emerging COVID-19 variant has of high risk of …
[HTML][HTML] Learning, visualizing and exploring 16S rRNA structure using an attention-based deep neural network
Recurrent neural networks with memory and attention mechanisms are widely used in
natural language processing because they can capture short and long term sequential …
natural language processing because they can capture short and long term sequential …
[HTML][HTML] Exploring thematic structure and predicted functionality of 16S rRNA amplicon data
Analysis of microbiome data involves identifying co-occurring groups of taxa associated with
sample features of interest (eg, disease state). Elucidating such relations is often difficult as …
sample features of interest (eg, disease state). Elucidating such relations is often difficult as …
[HTML][HTML] Keeping up with the genomes: efficient learning of our increasing knowledge of the tree of life
Background It is a computational challenge for current metagenomic classifiers to keep up
with the pace of training data generated from genome sequencing projects, such as the …
with the pace of training data generated from genome sequencing projects, such as the …
Interpretable and predictive deep modeling of the SARS-CoV-2 spike protein sequence
As the COVID-19 pandemic continues, the SARS-CoV-2 virus continues to rapidly mutate
and change in ways that impact virulence, transmissibility, and immune evasion. Genome …
and change in ways that impact virulence, transmissibility, and immune evasion. Genome …