Our previous studies demonstrated that 17β-estradiol (E2) rapidly induces the interaction of
estrogen receptor α (ERα) with the adapter protein Shc, the translocation of ERα to the cell …

Background: High doses of estrogen can promote tumor regression in postmenopausal
women with hormone-dependent breast cancer, but the mechanism is unknown. We …

Single-crystal X-ray diffraction is a powerful characterization technique that enables the
determination of atomic arrangements in crystalline materials. Growing or retaining large single …

Surface topography has been considered a difficult task for seismic wave numerical
modelling by the finite-difference method (FDM) because the most popular staggered finite-…

Afforestation has been accepted as a key measure for preventing soil erosion on the
Chinese Loess Plateau for 40 years. In this study, we assessed the ecological success of …

We describe a set of benchmark exercises that are designed to test if computer codes that
simulate dynamic earthquake rupture are working as intended. These types of computer …

This paper reports our large-scale nonlinear earthquake simulation software on Sunway
TaihuLight. Our innovations include: (1) a customized parallelization scheme that employs the …

This review provides insight into biomolecular knowledge regarding the non-genomic
actions of estrogen in hormone-dependent breast cancer, particularly its role in the rapid …

In this work, we fabricated PIM-based mixed matrix membranes (MMMs) containing MOF-801/ionic
liquid nanocomposites to enhance CO 2 separation performance of pure polymer …

We present an integrated model of an extranuclear, estrogen receptor-α (ERα)-mediated, rapid
MAPK activation pathway in breast cancer cells. In noncancer cells, IGF-I initiates a linear …