Methyl-CpG binding protein 2 (MeCP2) has crucial roles in transcriptional regulation and
microRNA processing 1 , 2 , 3 , 4 . Mutations in the MECP2 gene are found in 90% of patients …

Gene editing in model organisms has provided critical insights into brain development and
diseases. Here, we report the generation of a cynomolgus monkey (Macaca fascicularis) …

Background Repetitive Transcranial Magnetic Stimulation (rTMS)/ Deep-brain Magnetic
Stimulation (DMS) is an effective therapy for various neuropsychiatric disorders including major …

Objectives In this study, we aim to evaluate the effect of urban and rural resident medical
insurance scheme (URRMI) on the utilisation of medical services by urban and rural residents …

Whole-brain genome editing to correct single-base mutations and reduce or reverse behavioral
changes in animal models of autism spectrum disorder (ASD) has not yet been achieved…

Hypoxic-ischemic (HI) brain damage (HIBD) leads to high neonatal mortality and severe
neurologic morbidity. Autophagy is involved in the pathogenesis of HIBD. This study aims to …

Objective To investigate the effect of intraventricular injection of human dental pulp stem
cells (DPSCs) on hypoxic-ischemic brain damage (HIBD) in neonatal rats. Methods Thirty-six …

Although CRISPR/Cas9-mediated gene editing is widely applied to mimic human disorders,
whether acute manipulation of disease-causing genes in the brain leads to behavioral …

Background Atherosclerosis is an important cardiovascular disease, becoming a major and
increasing health problem in developed countries. However, the possible underlying …

Alginate oligosaccharides (AOs) prepared through enzymatic reaction by diverse alginate
lyases under relatively controllable and moderate conditions possess versatile biological …