User profiles for Zhibin Ning

Zhibin Ning

University of ottawa
Verified email at uottawa.ca
Cited by 4518

Bottom-up proteomics (2013–2015): keeping up in the era of systems biology

J Mayne, Z Ning, X Zhang, AE Starr, R Chen… - Analytical …, 2016 - ACS Publications
Over 17,000 papers related to proteomics have been published since our 2011− 2013 review.
A subset are true gems reporting amazing applications of proteomics to better understand …

MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain

…, N Fu, Z Yan, HY Hu, Y Xu, Y Yuan, Z Ning… - Genome …, 2010 - genome.cshlp.org
Changes in gene expression levels determine differentiation of tissues involved in development
and are associated with functional decline in aging. Although development is tightly …

Metaproteomic and metabolomic approaches for characterizing the gut microbiome

DL Peters, W Wang, X Zhang, Z Ning, J Mayne… - …, 2019 - Wiley Online Library
The gut microbiome has been shown to play a significant role in human healthy and diseased
states. The dynamic signaling that occurs between the host and microbiome is critical for …

Widespread splicing changes in human brain development and aging

…, YP Phoebe Chen, N Li, Y Hu, N Fu, Z Ning… - Molecular systems …, 2013 - embopress.org
While splicing differences between tissues, sexes and species are well documented, little is
known about the extent and the nature of splicing changes that take place during human or …

[HTML][HTML] Metaproteomics reveals associations between microbiome and intestinal extracellular vesicle proteins in pediatric inflammatory bowel disease

X Zhang, SA Deeke, Z Ning, AE Starr, J Butcher… - Nature …, 2018 - nature.com
Alterations in gut microbiota have been implicated in the pathogenesis of inflammatory
bowel disease (IBD), however factors that mediate the host–microbiota interactions remain …

[HTML][HTML] MetaPro-IQ: a universal metaproteomic approach to studying human and mouse gut microbiota

X Zhang, Z Ning, J Mayne, JI Moore, J Li, J Butcher… - Microbiome, 2016 - Springer
Background The gut microbiota has been shown to be closely associated with human
health and disease. While next-generation sequencing can be readily used to profile the …

[HTML][HTML] Proteomic and metaproteomic approaches to understand host–microbe interactions

…, L Li, X Zhang, R Daoud, J Ryan, Z Ning… - Analytical …, 2018 - ACS Publications
The human body is composed not only of human cells but is occupied by bacteria, archaea,
fungi, and viruses; this ensemble of organisms (microbiota) and their expressed genes are …

[HTML][HTML] MetaLab: an automated pipeline for metaproteomic data analysis

K Cheng, Z Ning, X Zhang, L Li, B Liao, J Mayne… - Microbiome, 2017 - Springer
Background Research involving microbial ecosystems has drawn increasing attention in
recent years. Studying microbe-microbe, host-microbe, and environment-microbe interactions …

Assessing the impact of protein extraction methods for human gut metaproteomics

X Zhang, L Li, J Mayne, Z Ning, A Stintzi, D Figeys - Journal of proteomics, 2018 - Elsevier
Metaproteomics is a promising methodology for the functional characterizations of the gut
microbiome. However, the performance of metaproteomic analysis is affected by protein …

[HTML][HTML] An in vitro model maintaining taxon-specific functional activities of the gut microbiome

L Li, E Abou-Samra, Z Ning, X Zhang, J Mayne… - Nature …, 2019 - nature.com
In vitro gut microbiome models could provide timely and cost-efficient solutions to study
microbiome responses to drugs. For this purpose, in vitro models that maintain the functional and …