The radiation-based sterile insect technique (SIT) has successfully suppressed field populations
of several insect pest species, but its effect on mosquito vector control has been limited. …

Genetic strategies that reduce or block pathogen transmission by mosquitoes have been
proposed as a means of augmenting current control measures to reduce the growing burden of …

We present a draft sequence of the genome of Aedes aegypti, the primary vector for yellow
fever and dengue fever, which at ∼1376 million base pairs is about 5 times the size of the …

Wolbachia is a maternally transmitted symbiotic bacterium of insects that has been
proposed as a potential agent for the control of insect-transmitted diseases. One of the major …

Mosquito species, members of the genera Aedes, Anopheles and Culex, are the major
vectors of human pathogens including protozoa (Plasmodium sp.), filariae and of a variety of …

Aedes aegypti, the mosquito vector of dengue viruses, utilizes its innate immune system to
ward off a variety of pathogens, some of which can cause disease in humans. To date, the …

Regulation of male sexual differentiation by a Y chromosome-linked male determining factor
(M-factor) is one of a diverse array of sex determination mechanisms found in insects. By …

Mosquitoes are vectors of parasitic and viral diseases of immense importance for public
health. The acquisition of the genome sequence of the yellow fever and Dengue vector, Aedes …

Transmission of malaria is dependent on the successful completion of the Plasmodium
lifecycle in the Anopheles vector. Major obstacles are encountered in the midgut tissue, where …

A proposed strategy to aid in controlling the growing burden of vector-borne disease is
population replacement, in which a natural vector population is replaced by a population with a …